Raphael Silva Rodrigues

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OBJECTIVE Comparative assessment of the mortality rates of two septic patients' ages and/or gender subgroups, admitted to the intensive care unit of a university hospital. METHODS From December 2005 to April 2008, from a total of 628 patients, 133 were admitted to the intensive care unit with sepsis and included into two age subgroups: (G1) 14 - 40 years(More)
BACKGROUND Clostridium difficile is an anaerobic bacterium that causes antibiotic-associated diarrhea. It produces toxin A and toxin B (TcdB), which cause injury to the gut epithelium. Glutamine is a fundamental fuel for enterocytes, maintaining intestinal mucosal health. Alanyl-glutamine (AQ) is a highly soluble dipeptide derivative of glutamine. We(More)
PURPOSE Human Immunodeficiency Virus (HIV) protease inhibitors (PI) remain a crucial component of highly active therapy (HAART) and recently have been demonstrated to have potent antitumor effect on a wide variety of tumor cell lines. However, discontinuation of therapy is an important issue, which may be related to various side-effects, especially(More)
Sepsis is a complex systemic response to infection characterized by multifactorial and interrelated defects in cardiopulmonary function and tissue metabolism.(1) Hemodynamic, systemic oxygen delivery and pulmonary gas exchange disorders have been intensively investigated, but the mechanisms behind gender-based differences in immune and hormonal(More)
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