Raphael Levine

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We removed the right olfactory bulb in neonatal mice, leaving the bulb on the left side intact as an internal control. At 5 days of survival time, we observed that the right cerebral hemisphere was displaced forward to occupy the region made vacant by removal of the bulb. The frontal cortex was, consequently, in close proximity to the lamina cribrosa. As a(More)
Electrolytic lesions were placed in the tractus septomesencephalicus (TSM) and tractus occipitomesencephalicus (TOM), efferent pathways originating in visual and somatosensorimotor areas of the avian telencephalon and distributing widely to brain stem and spinal nuclear regions. Lesion effects upon several aspects of ingestive behavior were examined using(More)
Gliomablastoma multiform (GBM) is the most fatal form of all brain cancers in humans. Currently there are limited diagnostic tools for GBM detection. Here, we applied surprisal analysis, a theory grounded in thermodynamics, to unveil how biomolecule energetics, specifically a redistribution of free energy amongst microRNAs (miRNAs), results in a system(More)
Please find below the published articles that we are aware of reporting the biochemical and functional validation of protein interactions discovered with Hybrigenics Yeast Two-Hybrid technology, ULTImate Y2H™. The mean impact factor for these 314 publications is 8.1 and the top 18 papers have an impact factor above 19. (2015). Cyclin C interacts with(More)
The intestinal tract, an organ of considerable complexity, requires application of numerous techniques for analysis of its physiology and perturbations by toxicologic agents. This review describes the methodology of importance in analysis of the absorptive function of the intestine and the transit of intestinal contents. Methods for studying absorption are(More)
1. The range of tricyclic antidepressant plasma levels (or doses) needed for therapeutic response remains largely unresolved, since quantal plasma concentration (or dose)--response relationships have not been clearly defined for either therapeutic or nontherapeutic effects. 2. The fact that certain patients apparently became more depressed at higher plasma(More)
Specific exclusion relations are know among the three Ustilago maydis viruses that are associated with the cytoplasmically transmitted 'killer phemomenon'. Of the three viruses P1, P4 and P6, only P1, and P4 cancoexist in one host cell. Mutual exclusion occurs between P1 and P6 and P4 unilaterally excludes P6. The exclusion relations were originally defined(More)
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