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Evaluation of the Transwell System for Characterization of Dissolution Behavior of Inhalation Drugs: Effects of Membrane and Surfactant.
- Marc Rohrschneider, Sharvari Bhagwat, R. Krampe, V. Michler, J. Breitkreutz, G. Hochhaus
- Chemistry, Medicine
- Molecular pharmaceutics
- 9 July 2015
Assessing the dissolution behavior of orally inhaled drug products (OIDs) has been proposed as an additional in vitro test for the characterization of innovator and generic drug development. A number… Expand
Interrelation between Disintegration, Dissolution and Permeation of Orodispersible Films (ODFs) Containing Ketoprofen
Sodium hydroxide solution as solvent transferred ketoprofen from the poorly soluble acidic form to the freely soluble sodium salt. Faster disintegration (500 µm: 9.67 s) and dissolution (release… Expand
Patient centric optimization of a successful soft mist inhaler