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In the present investigation, the behavioral, morphological, and histopathological effects of cypermethrin, a widely used synthetic pyrethroid insecticide, was ascertained in male and female albino rats (Rattus norvegicus). Cypermethrin administered at repeated oral doses of 5 and 20 mg/kg/day for 30 days produced varying degree of mild to moderate toxic(More)
The paper develops innovative methodology for robust and stable design of digital infinite impulse response (IIR) filters using a heuristic search method. The proposed heuristic search method enhances the capability to explore and exploit the search space locally as well globally to obtain optimal filter design parameters. A multicriterion optimization is(More)
Breast cancer survivors may experience long-term treatment complications, must live with the risk of cancer recurrence, and often experience psychosocial complications that require supportive care services. In low- and middle-income settings, supportive care services are frequently limited, and program development for survivorship care and long-term(More)
A Hybrid optimization algorithm is applied for designing stable infinite impulse response (IIR) digital filter based on L1-approximation error criterion. The proposed Hybrid method calculates the optimal filter coefficients by exploring and exploiting the search space locally as well globally. The filter designed based on L1-approximation error possesses(More)
A solution methodology for the design of digital infinite impulse response (IIR) filter considering multiple conflicting objectives has been proposed. The nucleus of the method is that multiple objectives can be attuned suitably, to optimize the performance in pass bands, stop bands and transition bands of IIR digital filters. The proposed method uses(More)
In the present study, a series of N-{4-[(4-amino-5-sulfanyl-4H-1,2,4-triazol-3-yl)methyl]-1,3-thiazol-2-yl}-2-substituted-amide (1a-d) derivatives were synthesized in good yields and characterized by IR, 1H NMR, mass spectral and elemental analyses. The compounds were evaluated for their preliminary in vitro antibacterial activity against Staphylococcus(More)
The present study deals with estimation of levels of fractions of serum glycoproteins, protein bound hexose (PBH), protein bound hexosamine (PBHex), protein bound fucose (PBF), protein bound sialic acid (PBS) and protein bound carbohydrate (PBC) in thirty patients of Major Depressive Disorders (MDD) in comparison with thirty normal subjects. In patients of(More)
In this paper, an optimal design of linear phase digital finite impulse response (FIR) filter using Modified Particle Swarm Optimization (MPSO) has been presented. In the design process, the filter length, pass band and stop band frequencies, pass band and stop band ripple sizes are specified. Sometimes the gradient based optimization techniques are not(More)
A novel clubbed triazolyl thiazole series of cdk5/p25 inhibitors, potentially useful for the treatment of Alzheimer's disease, is disclosed. Evaluation of the SAR of substitution within these series has allowed the identification of a range of compounds which significantly reduce brain cdk5/p25 and thus have potential as possible treatments for Alzheimer's(More)
Survival following a diagnosis of cancer is contingent upon an interplay of factors, some non-modifiable (e.g., age, sex, genetics) and some modifiable (e.g., volitional choices) but the majority determined by circumstance (personal, social, health system context and capacity, and health policy). Accordingly, mortality and survival rates vary considerably(More)