Randy Hartline

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Free-moving mice from the high-alcohol preference C57BL/6J strain and low-preference DBA/2J strain were slowly fed [2-14C]ethanol intragastrically until anesthesia was achieved. Behavior was monitored in a Plexiglas metabolic chamber while 14CO2 was simultaneously trapped to determine the rate of ethanol metabolism. Average time to the loss of the righting(More)
In vitro effects of ethanol on calcium taken up by synaptosomes were examined in two strains of mice, C57BL and DBA, that exhibit marked differences in alcohol sensitivity and preference. There were no significant strain differences in basal or depolarization-dependent synaptosomal calcium levels. Ethanol did not reduce the basal calcium level but instead(More)
The successful implementation of a Flexible Manufacturing/Assembly System can be an effective means of reducing labor, resources and work-in-process inventory. It can increase equipment utilizations, improve quality and result in increased throughput. Simulation is an effective tool for analyzing critical system components and their inter-relationships;(More)
Mice from the high-ethanol preferring C57BL strain and low-ethanol preferring DBA strain were tested for their preference for butanediols. The C57BL strain showed a significantly higher preference for a 10% (v/v) solution of 1,3-butanediol than the DBA strain. The C57BL strain also showed a significantly greater consumption of 1,2- and 2,3-butanediol, but(More)
Expired ethanol and acetaldehyde were measured after an oral injection of ethanol in C57BL/6J and DBA/2J mouse strains by a combination of several techniques in a sequence involving a method for trapping expired radioactive compounds, separation of compounds by gas chromatography, isolation of radioactive ethanol and acetaldehyde, and their quantitative(More)
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