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Dillenia indica L. attenuates diabetic nephropathy via inhibition of advanced glycation end products accumulation in STZ-nicotinamide induced diabetic rats
The present study was aimed to evaluate advanced glycation end products (AGEs) inhibitory activity of alcohol and hydro-alcohol extract (DAE and DHE) of Dillenia indica L. (Family: Dilleniaceae) andExpand
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Selective β1‐adrenoreceptor blocking activity of newly synthesized acyl amino‐substituted aryloxypropanolamine derivatives, DPJ 955 and DPJ 890, in rats
The in‐vivo β‐adrenoreceptor antagonistic activity of test compounds DPJ 955 and DPJ 890 was assessed against β‐adrenoreceptor agonist (isoprenaline) induced tachycardia in anaesthetized rats. TheExpand
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Chemical constituents from the leaves of Boehmeria rugulosa with antidiabetic and antimicrobial activities
Three new flavonoid glycosides, named chalcone-6′-hydroxy-2′,3,4-trimethoxy-4′-O-β-d-glucopyranoside (1), isoflavone-3′,4′,5,6-tetrahydroxy-7-O-{β-d-glucopyranosyl-(1 → 3)-α-l-rhamnopyranoside} (2),Expand
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Anti-hyperglycemic Effect of Stephania Glabra Tubers in Alloxan Induced Diabetic Mice
Different doses of ethanolic extract of Stephania glabra tuber were evaluated for antihyperglycemic activity in alloxan induced diabetic mice. The oral administration of 100, 200 and 500 mg/kg bodyExpand
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Impact of obesity on hypertension-induced cardiac remodeling: role of oxidative stress and its modulation by gemfibrozil treatment in rats.
This study investigated the possible synergistic role of obesity in hypertension-induced cardiac remodeling and its modulation by gemfibrozil treatment in rats. Male Wistar rats were fed a high-fatExpand
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Anti-hyperglycemic effect of 11-hydroxypalmatine, a palmatine derivative from Stephania glabra tubers
A palmatine derivative, named 11-hydroxypalmatine (4), has been isolated from the tubers of Stephania glabra, together with three known alkaloids, palmatine (1), dehydrocorydalmine (2), andExpand
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Study of β-Adrenoreceptor Antagonistic Activity of DPJ 904 in Rats
β-Adrenoreceptor antagonistic activity of a newly synthesized compound was evaluated in vivo by measuring the mean arterial blood pressure and heart rate of urethane-anesthetized rats treated withExpand
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Modulation of impact of high fat diet in pathological and physiological left ventricular cardiac hypertrophy by fluvastatin.
The male Wistar rats were kept at high fat diet for 90 days and subjected to partial abdominal aortic constriction (PAAC) at 62nd and continued up to 90th day. Similarly, rats were kept at high fatExpand
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Toxicity, Spectroscopic Characterization and Electrochemical Behaviour of New Macrocclic Complexes of Lead(II) and Palladium(II) Metals
Tetraazamacrocyclie complexes of lead and palladium have been synthesized by the template process using the bis(benzil)ethylenediamine precursor. The tetradentate macrocycle (maL) reacts with PbCl2,Expand
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