Ranajit Ghose

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The backbone dynamics of the N-terminal domain of the chaperone protein Escherichia coli DnaJ have been investigated using steady-state 1H-15N NOEs, 15N T1, T2, and T1 rho relaxation times, steady-state 13C alpha-13CO NOEs, and 13CO T1 relaxation times. Two recombinant constructs of the N-terminal domain of DnaJ have been studied. One, DnaJ(1-78), contains(More)
The effects of cross-correlation between Curie spin-nuclear dipole and nuclear dipole-nuclear dipole interactions on the linewidths and resonance frequencies of the individual lines of an AX multiplet in paramagnetic systems have been calculated. The implication of the relaxation-induced frequency shift of the lines (dynamic frequency shift) for the(More)
We present a simple method for extracting interference effects between chemical shift anisotropy (CSA) and dipolar coupling from spin relaxation measurements in macromolecules, and we apply this method to extracting cross-correlation rates involving interference of amide 15N CSA and 15N-1H dipolar coupling and interference of carbonyl 13C' CSA and 15N-13C'(More)
Heteronuclear NMR methods have been used to elucidate the secondary structure and the general tertiary fold of the protein NodF from Rhizobium leguminosarum. A similarity to acyl carrier proteins of the fatty acid synthase system had been suggested by the presence of a phosphopantetheine prosthetic group and a short stretch of sequence homology near the(More)
We have investigated the underlying assumptions in estimating cross-correlation rates between chemical shift anisotropy (CSA) and dipolar coupling mechanisms in a scalar-coupled two-spin IS system, from laboratory frame relaxation experiments. It has ben shown that for an arbitrary relaxation delay, the difference in relaxation rates of the individual(More)
Seismic interferometry is the process of generating new seismic traces from the crosscorrelation, convolution or deconvolution of existing traces. One of the starting assumptions for deriving the representations for seismic interferometry by crosscorrelation is that there is no intrinsic loss in the medium where the recordings are performed. In practice,(More)
In geophysical exploration different types of measurements are used to probe the same subsurface region. In this paper we show that the wavelet transform can aid the process of linking different data types. The continuous wavelet transform, and in particular the analysis of amplitudes along wavelet transform modulus maxima lines, is a powerful tool to(More)
A careful look into the pertinent models of poroelasticity reveals that in water-saturated sediments or soils, the seismic (P and S wave) velocity dispersion and attenuation in the low field-seismic frequency band (20-200 Hz) have a contrasting behavior in the porosity-permeability domain. Taking advantage of this nearly orthogonal behavior, a new approach(More)
The angle Theta(C(alpha)H(alpha)),NH(N) subtended by the internuclear vectors 13C(alpha)-H(alpha) and 15N-H(N) in doubly-labeled proteins can be determined by observing the effect of cross-correlation between the dipolar interactions on zero- and double-quantum coherences involving 13C(alpha) and 15N. Two complementary 2D experiments with the appearance of(More)
HOHAHA distortions in conventional (CW) ROESY experiments are known to be prominent when the frequency of the spin-lock field is near the midpoint between the resonance frequencies of a pair of coupled spins. That the disappearance of these distortions with offset from the midpoint is more rapid for large molecules than smaller ones is less widely known,(More)