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A wide range of cell stresses, including DNA damage, signal to p53 through posttranslational modification of p53. The cytoplasmic functions of p53 are emerging as an important constituent of role of p53 in tumor suppression. Here, we report that deletion of the Cul9 (formerly Parc) gene, which encodes an E3 ubiquitin ligase that binds to p53 and localizes(More)
With the advancement of distributed sensing technologies, abundant data are generated in rolling processes. While these data contain rich information about the process and product, it is a challenging task to develop a systematic method to model the relationship between process and product quality variables for quality improvements. This paper addresses(More)
Metamorphic malware is able to change its signature which is a fixed sequence of bytes or code from generation to generation. This makes the traditional scanner based on the signature difficult to detect it. Combing normalization with traditional scanner is a promising direction to solve the problem. The idea is: firstly transform the code into canonical(More)
Spectral clustering algorithm has proved be more effective than most traditional algorithms in finding clusters. However, its high computational complexity limits its effect in actual application. This paper combines the spectral clustering with MapReduce, through evaluation of sparse matrix eigenvalue and computation of distributed cluster, puts forward(More)
Reconfigurable assembly systems enable a family of products to be assembled in a single system by adjusting and reconfiguring fixtures according to each product. The sharing of fixtures among different products impacts their robustness to fixture variation due to trade offs in fixture design (to allow the accommodation of the family in the single system)(More)
The article aims at providing theoretical foundation for security of moxibustion through analyzing chemical compositions of Artemisia Argyi of different years from Qichun County, Hubei Province, and moxa wool refined in different proportions. Artemisia Argyi from Qichun on 2007, 2008 and 2009 were taken as raw materials, and processed into moxa wool with(More)