Ramya Mallampati

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The aim of this study was to understand the skin irritation effects of saturated aliphatic hydrocarbons (HCs), C9-C16, found jet fuels using in vitro 3-dimensional EpiDerm full thickness-300 (EFT-300) skin cultures. The EFT-300 cultures were treated with 2.5microl of HCs and the culture medium and skin samples were collected at 24 and 48h to measure the(More)
In the present study we made an attempt to understand the skin irritation cascade of selected aliphatic hydrocarbons using microdialysis technique. Microdialysis probes were inserted into dermis in the dorsal skin of hairless rats. After 2h of probes insertion, occlusive dermal exposure (2h) was carried out with 230 microl of nonane, dodecane and(More)
Keeping as many variables as possible constant, several indices of reproductive function were examined in female rats androgenized by different methods. The age at which vaginal opening occurred, the incidence of persistent estrus, the ovarian, uterine, adrenal, and pituitary weights, and the pituitary and serum gonadotropin (FSH, LH, prolactin)(More)