Ramy R. Attia

Learn More
Striking individual differences in severity of group A streptococcal (GAS) sepsis have been noted, even among patients infected with the same bacterial strain. We had provided evidence that HLA class II allelic variation contributes significantly to differences in systemic disease severity by modulating host responses to streptococcal superantigens.(More)
Individuals infected with genetically identical group A streptococcal (GAS) strains develop starkly different disease progression and outcome [1]. We reported that HLA class II allelic variation contributes to differences in sys-temic disease severity by modulating host responses to streptococcal superantigens [2]. Inasmuch as the bacteria produce(More)
  • 1