Learn More
OBJECTIVE To review the epidemiology and characteristics of patients who died or underwent colectomy secondary to fulminant Clostridium difficile colitis. SUMMARY BACKGROUND DATA In patients with C. difficile colitis, a progressive, systemic inflammatory state may develop that is unresponsive to medical therapy; it may progress to colectomy or death. (More)
BACKGROUND Acute renal failure (ARF) is a serious complication that contributes to patient morbidity and may result in death. To date, no data are available regarding the predictive risk of ARF or its effect on the outcome of patients who undergo laparoscopic gastric bypass. METHODS The medical records of 1800 patients who underwent gastric bypass from(More)
BACKGROUND Despite the relatively high incidence of ventral hernias in the morbidly obese, their management in bariatric surgery patients remains difficult and controversial. We sought to define a rational approach to ventral hernia management in the gastric bypass patient in a university hospital setting. METHODS We performed a retrospective,(More)
BACKGROUND There is no consensus regarding the optimal treatment of ventral hernias in patients who present for weight loss surgery. METHODS Medical records of consecutive morbidly obese patients who underwent laparoscopic Roux-en-Y (LRYGB) gastric bypass with a secondary diagnosis of ventral hernia were reviewed. Only patients who were beyond 6 months of(More)
BACKGROUND There has been limited research examining the mechanisms and epidemiology of sexual dysfunction in the morbidly obese. Our objectives were to measure sexual function in the morbidly obese man before and after substantial weight loss induced by gastric bypass surgery. STUDY DESIGN All male patients in undergoing gastric bypass completed the(More)
We investigated the in vitro effects of combining interleukin-18 (IL-18) and IL-2 on human lymphocytes. The combined use of these two cytokines synergistically enhanced the proliferation, cytolytic activity, and interferon-gamma production of peripheral blood mononuclear cells. Phenotypic analysis revealed a preferential expansion of CD56+CD3- cells and an(More)
BACKGROUND To determine the effect of different stoma sizes on the percent excess weight loss (%EWL) following laparoscopic Roux-en-Y gastric bypass surgery (LRYGBP). METHODS Blinded randomized prospective controlled study in two American Society for Bariatric Surgeons-designated Centers of Excellence hospitals. Two hundred gastric bypass patients between(More)
Over the past ten years, the identification of the critical role that dendritic cells (DCs) play in stimulating a specific immune response has led to their use in cancer and HIV therapy. Interesting responses have been reported but the most effective approach and the duration of these responses are still unclear. The quality of DCs, the means by which tumor(More)
BACKGROUND The routine use of closed suction drains and upper GI (UGI) series has been used to aid in the diagnosis and management of gastrojejunal leak after gastric bypass as well as diagnose intra-abdominal bleeding. MATERIALS AND METHODS 352 consecutive laparoscopic gastric bypass procedures were performed without the use of routine drains or(More)
BACKGROUND To review the short-term safety and efficacy of the laparoscopic adjustable gastric band (LAGB) and laparoscopic gastric bypass (GBP) in patients older than 65 years. METHODS A single-institution review of all bariatric procedures was performed. RESULTS Twenty-seven patients were identified. Of the 27 patients, 13 underwent primary GBP and 14(More)