Ramon Peçanha

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This study tests the hypothesis that bone marrow-derived mononuclear cell (BMDMC) therapy may reduce lung inflammation and fibrosis leading to an improvement in respiratory mechanics in a murine model of silicosis. 52 female C57BL/6 mice were randomly assigned into four groups. In the silica group (SIL), silica suspension (20 mg/50 μL in saline) was(More)
A prospective comparison of laparoscopic (Group 1 = 18 patients) and conventional (Group 2 = 18 patients) abdominoperineal resection in patients with low rectal cancer was carried out. Parameters studied included the length of the procedure, ileus, and hospitalization; the rate of conversion; and the morbidity and mortality rates. The mean (SD) operating(More)
BACKGROUND The aim of the present study was to investigate whether adipose-derived stem cells could contribute to skeletal muscle-healing. METHODS Adipose-derived stem cells of male rats were cultured and injected into the soleus muscles of female rats. Two and four weeks after injections, muscles were tested for tetanic force (50 Hz). Histological(More)
The hypothalamic-pituitary-thyroid axis is affected by acute exercise, but the mechanisms underlying thyroid function changes after exercise remain to be defined. The aim of this study was to elucidate the effects of a session of acute exercise on the treadmill at 75% of maximum oxygen consumption on thyroid function of rats. Male Wistar rats were divided(More)
Granulocyte colony-stimulating factor (G-CSF) has been reported to improve cardiac performance by increasing the number of bone marrow stem cell in the peripheral circulation. The aim of this study was to investigate the impact of G-CSF administration on cardiac function in a rat model of acute myocardial infarction. Recombinant human G-CSF (Filgrastim, 100(More)
Microbiological acid solutions produced byThiobacillus ferrooxidans andThiobacillus thiooxidans on pyritiferous concentrate were used to solubilize phosphate rock with a high grade in P2O5. Five different mixtures of pyritiferous concentrate and phosphate rock, in different proportions, were used in adequate liquid culture media. Phosphate solubilization(More)
Skeletal muscle injury is the most common problem in orthopedic and sports medicine, and severe injury leads to fibrosis and muscle dysfunction. Conventional treatment for successive muscle injury is currently controversial, although new therapies, like cell therapy, seem to be promise. We developed a model of successive injuries in rat to evaluate the(More)
The centrifugation equilibrium problem is formulated and solved using a new procedure in which the specified variables are the temperature, system volume, particle dimensions and concentrations, angular speed, cell length, and cell distance from the rotation axis. As a result, we obtain the concentration profiles for all types of particles present in the(More)
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