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  • Akın Akıncıoğlu, Ebutalib Kocaman, +5 authors Süleyman Göksu
  • Chemistry, Medicine
  • Bioorganic chemistry
  • 2017 (First Publication: 1 October 2017)
  • In this study, a series of novel β-benzylphenethylamines and their sulfamide derivatives were synthesized starting from (Z)-2,3-diphenylacrylonitriles. Pd-C catalysed hydrogenation ofExpand
  • Serdar Durdagi, Ismail Erol, Ramin Ekhteiari Salmas, Busecan Aksoydan, Isik Kantarcioglu
  • Biology, Medicine
  • Neuroscience Letters
  • 2019 (First Publication: 1 May 2019)
  • G Protein-Coupled Receptors (GPCRs) can form homo- and heterodimers or constitute higher oligomeric clusters with other heptahelical GPCRs. In this article, multiscale molecular modeling approachesExpand
  • Ramin Ekhteiari Salmas, Mine Yurtsever, Matthias Stein, Serdar Durdagi
  • Medicine, Chemistry
  • Molecular Diversity
  • 2015 (First Publication: 5 February 2015)
  • Homology model structures of the dopamine D2 receptor (D2R) were generated starting from the active and inactive states of $$\upbeta $$β2-adrenergic crystal structure templates. To the best of ourExpand
  • Süleyman Göksu, Ali Asghar Shafi Naderi, +5 authors Ramin Ekhteiari Salmas
  • Medicine, Chemistry
  • Bioorganic chemistry
  • 2014 (First Publication: 1 October 2014)
  • In this study, a series of sulfamoyl carbamates and sulfamide derivatives were synthesized. Six commercially available benzyl amines and BnOH were reacted with chlorosulfonyl isocyanate (CSI) to giveExpand
  • Bünyamin Özgeriş, Süleyman Göksu, +5 authors Claudiu T. Supuran
  • Medicine, Chemistry
  • Bioorganic & medicinal chemistry
  • 2016 (First Publication: 15 May 2016)
  • In the present study a series of urea and sulfamide compounds incorporating the tetralin scaffolds were synthesized and evaluated for their acetylcholinesterase (AChE), human carbonic anhydrase (CA,Expand
  • Serdar Durdagi, Ramin Ekhteiari Salmas, Matthias Stein, Mine Yurtsever, Philip Seeman
  • Medicine, Chemistry
  • ACS chemical neuroscience
  • 2016 (First Publication: 17 February 2016)
  • We have recently reported G-protein coupled receptor (GPCR) model structures for the active and inactive states of the human dopamine D2 receptor (D2R) using adrenergic crystal structures asExpand
  • Georgios Leonis, Aggelos Avramopoulos, Ramin Ekhteiari Salmas, Serdar Durdagi, Mine Yurtsever, Manthos G. Papadopoulos
  • Chemistry, Medicine, Computer Science
  • J. Chem. Inf. Model.
  • 2014 (First Publication: 25 July 2014)
  • Opioid G protein-coupled receptors (GPCRs) have been implicated in modulating pain, addiction, psychotomimesis, mood and memory, among other functions. We have employed the recently reported crystalExpand
  • Shaher Bano Mirza, Ramin Ekhteiari Salmas, M Qaiser Fatmi, Serdar Durdagi
  • Medicine, Biology
  • Journal of molecular graphics & modelling
  • 2016 (First Publication: 1 May 2016)
  • Dengue virus is a major issue of tropical and sub-tropical regions. Dengue virus has been the cause behind the major alarming epidemics in the history with mass causalities from the decades.Expand
  • Tahsin F. Kellici, Dimitrios Ntountaniotis, +12 authors Thomas M. Mavromoustakos
  • Chemistry, Medicine
  • Current medicinal chemistry
  • 2016 (First Publication: 31 December 2015)
  • The angiotensin II type 1 receptor (AT1R) has been recently crystallized. A new era has emerged for the structure-based rational drug design and the synthesis of novel AT1R antagonists. In thisExpand