Ramgopal Mettu

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We consider an algorithm to maintain the connected components and the biconnected components of a graph where vertex and edge insertions are allowed. Algorithms for this problem can be applied to task decomposition in engineering design. Connected components are maintained using a disjoint set data structure and the biconnected components are maintained by(More)
T-cell CD4+ epitopes are important targets of immunity against infectious diseases and cancer. State-of-the-art methods for MHC class II epitope prediction rely on supervised learning methods in which an implicit or explicit model of sequence specificity is constructed using a training set of peptides with experimentally tested MHC class II binding(More)
We describe our implementation of an algorithm to maintain the connected components and the biconnected components of a graph where vertex and edge insertions are allowed. Algorithms for this problem can be applied to task decomposition in engineering design. Connected components are maintained using a disjoint set data structure and the biconnected(More)
UNLABELLED Helper T-cell epitope dominance in human immunodeficiency virus type 1 (HIV-1) envelope glycoprotein gp120 is not adequately explained by peptide binding to major histocompatibility complex (MHC) proteins. Antigen processing potentially influences epitope dominance, but few, if any, studies have attempted to reconcile the influences of antigen(More)
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