Rama Gurram

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One of the main reasons considered for BCG failure in tuberculosis-endemic areas is impediment by environmental mycobacteria in its processing and generation of memory T-cell response. To overcome this problem, we developed a unique lipopeptide (L91) by linking the promiscuous peptide (sequence 91-110) of 16 kDa antigen of Mycobacterium tuberculosis to(More)
Today's wiki engines are not interoperable. The rendering engine is tied to the processing tools which are tied to the wiki editors. This is an unfortunate consequence of the lack of rigorously specified standards. This paper discusses an EBNF-based grammar for Wiki Creole 1.0, a community standard for wiki markup, and demonstrates its benefits. Wiki Creole(More)
Mycobacterium tuberculosis (M. tuberculosis) in latently infected individuals survives and thwarts the attempts of eradication by the immune system. During latency, Acr1 is predominantly expressed by the bacterium. However, whether M. tuberculosis exploits its Acr1 in impairing the host immunity remains widely unexplored. Hence, currently we have(More)
Today's wiki engines are not interoperable. This is an unfortunate consequence of the lack of rigorously specified standards. This technical report presents a complete and validated EBNF-based grammar for Wiki Creole, a community standard for wiki markup. Wiki Creole is also the only standard currently available. Wiki Creole is being specified using prose,(More)
Cytokines play a very important role in the regulation of immune homeostasis. Regulatory T cells (Tregs) responsible for the generation of peripheral tolerance are under the tight regulation of the cytokine milieu. In this study, we report a novel role of a bipyridyl compound, Caerulomycin A (CaeA), in inducing the generation of Tregs. It was observed that(More)
BACKGROUND Caerulomycin A (CaeA) is a known antifungal and antibiotic agent. Further, CaeA is reported to induce the expansion of regulatory T cell and prolongs the survival of skin allografts in mouse model of transplantation. In the current study, CaeA was purified and characterized from a novel species of actinomycetes, Actinoalloteichus spitiensis. The(More)
abstract Real-time location applications are mainly desktop based and costly for development and maintenance. In this project we worked on a Web service based architecture for monitoring and driving real-time analysis of fire truck missions. We used Web 2.0 technologies on the client side and SAP NetWeaver enterprise service oriented platform on the server(More)