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BACKGROUND Patients with obstructive sleep apnea syndrome (OSAS) are at increased risk for cerebrovascular diseases. The underlying mechanisms remain obscure. It may occur through a reduction in cerebral vascular reactivity. Continuous positive airway pressure (CPAP) is effective in reducing the occurrence of apneas. We hypothesized that treatment with CPAP(More)
According to recent epidemiologic studies, patients with sleep apnea/hypopnea syndrome (SAHS) are at increased risk of cardiovascular diseases, including stroke. However, the mechanisms are not well defined. Nocturnal apneas can trigger acute cerebral ischemia in predisposed patients and impaired vasodilatation is present in SAHS, but few studies have(More)
The diagnosis of Goodpasture's syndrome is established by the clinical setting of diffuse alveolar hemorrhage and glomerulonephritis, and the demonstration of circulating or tissue-bound antibasement membrane antibodies. However, cases of Goodpasture's syndrome limited either to the lungs or kidneys have been reported. The absence of immune deposits from(More)
BACKGROUND Cerebral vasoreactivity in obstructive sleep apnea syndrome is altered. Continuous positive airway pressure is effective in the reduction of the occurrence of apneas. We studied whether this treatment also improves cerebral vasoreactivity. METHODS The breath-holding maneuver was performed and assessed by apnea test with transcranial Doppler in(More)
INTRODUCTION Obstructive sleep apnea syndrome (OSAS) is characterized in polysomnography by recurrent airflow obstruction during sleep. The underlying pathogenic mechanisms of neuropsychological and cerebrovascular events in patients with OSAS have not been clarified unequivocally. MATERIAL AND METHODS Case-control study to evaluate the cerebral vasomotor(More)
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