Ralph Sörbris

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Microcalorimetry has been employed to measure the heat production by adipocytes obtained by percutaneous biopsy from lean subjects and from obese subjects before and after weight reduction. Cellular heat production was significantly lower in obese than in lean subjects. After weight reduction cellular heat production increased in fat cells from the obese(More)
In a retrospective analysis of 819 patients operated on for gallbladder disease, the costs and mortality rates were compared for 2 different strategies: (a) routine use of intraoperative cholangiography, or (b) selective use of intraoperative cholangiography on patients fulfilling at least 1 of 4 common clinical criteria. Selective use led to lower costs(More)
The relationship between obesity and alterations in adipose tissue metabolism and lipid transport was studied in fourteen obese subjects before and after a weight reduction of 4-22 kg. Blood glucose and plasma insulin patterns after peroral glucose intake improved significantly, and plasma glucagon levels decreased markedly after treatment. Plasma(More)
We have studied effects of weight reduction after gastroplasty on glucose and lipid metabolism in 15 grossly obese subjects. Their body weight decreased from 127 +/- 13 to 97 +/- 14 kg 6 months after surgery and remained essentially stable 8 months later. There was a marked improvement of lipid and carbohydrate metabolism with significant reductions in(More)
The effects of vegetarian fasting were evaluated in 14 grossly obese patients who participated in a program comprising 5 weeks' fasting in a lactovegetarian health center. Before and after the fasting period the patients were hospitalized and put on a standardized weight-maintaining diet; at the health center they consumed vegetable juices containing less(More)
The effect of five weeks fasting on body weight, lean body mass and fat weight was studied in 14 obese subjects (BW 92-200 kg, Broca's index 1.3-2.4). Before and after treatment the patients were hospitalized and put on a standardized weight maintaining diet, and variables reflecting thyroid function were compared before and after weight reduction. There(More)
Fifteen grossly obese patients were studied before and 6-8 months after gastroplasty. Their mean body weight decreased by 30% (from 127 +/- 13 to 97 +/- 14 kg, mean +/- SD). The preoperative hyperinsulinemia, hyperglucosemia and hyperglucagonemia were significantly reduced at follow up. Liproprotein lipase activity, measured in post-heparin plasma, was(More)
A method for the quantitative measurement of heat production in isolated human adipocytes is described. Fat cells are isolated by collagenase treatment of biopsy specimens of adipose tissue, and heat production measured by microcalorimetry. The heat effect was constant for at least 4 h. Heat values increased with increasing pH (about 6% per 0.1 pH unit) and(More)
Twenty-four grossly obese patients were operated on with horizontal gastroplasty. One patient died postoperatively of pulmonary embolism. The remaining 23 were extensively studied before and repeatedly after surgery. Eighteen months postoperatively the average weight loss was 34.4 kg (range, 1-71 kg). Seven patients had a weight reduction of less than 20%(More)
The costs for elective cholecystectomies were measured 1955, 1965 and 1975. The average length of stay decreased by 25% between 1955 and 1965 and with the same amount between 1965 and 1975. In spite of these marked reductions in the average length of stay there was only a significant decrease in costs between 1955 and 1965 but not between 1965 and 1975.