Ralph E. Stanton

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A new method of treatment planning for the I-125 and Pd-103 permanent interstitial prostate implant is developed, which does not use the traditional nomograms but automatically generates optimized source configurations. An iterative algorithm is used that places one seed at a step. The volume dose of target is calculated at each step to determine the(More)
An Hadamard matrix H is an n by n matrix all of whose entries are +1 or — 1 which satisfies HH T = n J, H T being the transpose of H. The order n is necessarily 1, 2 or 42, with t a positive integer. R. E. A. C. Paley [3] gave construction methods for various infinite classes of Hadamard matrices, chiefly using properties of quadratic residues in finite(More)
A Costas latin square of order n is a set of n disjoint Costas arrays of the same order. Costas latin squares are studied here from a construction as well as a classification point of view. A complete classification is carried out up to order 27. In this range, we verify the conjecture that there is no Costas latin square for any odd order n ≥ 3. Various(More)
A graph is singular if the zero eigenvalue is in the spectrum of its 0-1 adjacency matrix A. If an eigenvector belonging to the zero eigenspace of A has no zero entries, then the singular graph is said to be a core graph. A (κ, τ)-regular set is a subset of the vertices inducing a κ-regular subgraph such that every vertex not in the subset has τ neighbours(More)
How do enzymes achieve very large rate enhancements compared to corresponding uncatalyzed reactions in solution? We present a computational approach which combines high-level ab initio quantum mechanical calculations with classical free energy calculations to address this question. Our calculations lead to accurate estimates of DeltaG for both trypsin and(More)
A breast phantom of novel design has been used to measure visibility of simulated calcific and soft-tissue fibrillar details in mammography, as well as to determine the roentgen exposure vs. depth. Exposure data were combined with a model of the breast as compressed during mammography to compute the mean exposure to the ductal parenchyma (MDE). Three(More)
The most commonly used method of calibrating high-energy photon or electron beams consists in converting cavity ionization to dose by the application of the appropriate Clambda or CE multipled by the 60Co correction factor. The correct interpretation of calibration data for pulsed photon or electron beams requires a knowledge of the charge collection(More)
There is a major gap in backscatter information for diagnostic x-ray beams. Such information is increasingly needed for dose measurements and calculations, as well as for designing devices and techniques. We have therefore carried out measurements on both low Z materials and metals, using an ion chamber method designed specifically for the purpose. Lucite(More)