Ralf Surber

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AIMS The aim of the present study was to elucidate the molecular mechanism underlying the concomitant occurrence of cardiac conduction disease and long QT syndrome (LQT3), two SCN5A channelopathies that are explained by loss-of-function and gain-of-function, respectively, in the cardiac Na+ channel. METHODS AND RESULTS A Caucasian family with prolonged QT(More)
AIMS To examine the effect of renal denervation (RDN) on 24‑h ambulatory blood pressure (ABP) with a standard radiofrequency ablation catheter (RF catheter). METHODS Seventy-five patients with resistant hypertension received bilateral RDN with an RF catheter (6 RF applications, 1 minute each, 8-12 watts). Seventy patients fulfilled inclusion criteria with(More)
Running title: LQT3 and CCD caused by a novel hNa v 1.5 mutation Abstract Aims-The aim of the present study was to elucidate the molecular mechanism underlying the concomitant occurrence of cardiac conduction disease (CCD) and long QT syndrome (LQT3), two SCN5A channelopathies that are explained by loss-of-function and gain-of-function, respectively, in the(More)
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