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  • Ralf Küppers
  • Biology, Medicine
  • Nature Reviews Cancer
  • 2005 (First Publication: 1 April 2005)
  • Chromosomal translocations involving the immunoglobulin loci are a hallmark of many types of B-cell lymphoma. Other factors, however, also have important roles in the pathogenesis of B-cellExpand
  • Ulf Klein, Klaus Rajewsky, Ralf Küppers
  • Medicine, Biology
  • The Journal of experimental medicine
  • 1998 (First Publication: 2 November 1998)
  • Immunoglobulin (Ig)M+IgD+ B cells are generally assumed to represent antigen-inexperienced, naive B cells expressing variable (V) region genes without somatic mutations. We report here that humanExpand
  • Ralf Küppers
  • Biology, Medicine
  • Nature Reviews Cancer
  • 2009
  • Hodgkin's lymphoma was first described in 1832. The aetiology of this lymphoma, however, remained enigmatic for a long time. Only within the past 10 years has the B-cell nature of the pathognomonicExpand
  • Verena Brune, Enrico Tiacci, +10 authors Ralf Küppers
  • Biology, Medicine
  • The Journal of experimental medicine
  • 2008 (First Publication: 29 September 2008)
  • The pathogenesis of nodular lymphocyte-predominant Hodgkin lymphoma (NLPHL) and its relationship to other lymphomas are largely unknown. This is partly because of the technical challenge of analyzingExpand