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Ovarian hyperstimulation syndrome (OHSS) is a rare and potentially life-threatening complication during controlled ovarian stimulation. It can be associated with severe morbidity and may even be fatal. The etiology of the condition and predisposing factors are still not fully understood. Data concerning pathophysiology in patients with OHSS were searched(More)
OBJECTIVE To describe the first live birth after transplantation of ovarian tissue following overnight transportation of the tissue before freezing. DESIGN Technical note. SETTING University department of obstetrics and gynecology. PATIENT(S) A 25-year-old cancer survivor with previous Hodgkin disease and relapse. INTERVENTION(S) The ovarian tissue(More)
PURPOSE Fertility preservation methods are playing an increasing role in women up to the age of 40 years because of rising survival rates in those affected by cancer. However, balanced practical recommendations concerning all relevant fertility preservation, to support doctors in counselling and treating patients, are still rare. METHODS These(More)
BACKGROUND The major pathophysiologic changes observed in preeclampsia suggest that endothelial cell dysfunction plays an important role in this disorder. The pathway mediating endothelial cell layer dysfunction is unknown. The concentration of endothelin-1 (ET-1), a potent mammalian vasoconstrictor peptide produced by the vascular endothelium, has been(More)
STUDY QUESTION What is the success rate in terms of ovarian activity (menstrual cycles) as well as pregnancy and delivery rates 1 year after orthotopic ovarian transplantations conducted in a three-country network? SUMMARY ANSWER In 49 women with a follow-up >1 year after transplantation, the ovaries were active in 67% of cases and the pregnancy and(More)
BACKGROUND Spontaneous cervical artery dissection (sCAD) in multiple neck arteries (polyarterial sCAD) is traditionally thought to represent a monophasic disorder suggesting nearly simultaneous occurrence of the various intramural hematomas. Its incidence ranges from 10 to 28%. The recurrence rate of sCAD in general over up to 8.6 years has been recorded to(More)
INTRODUCTION It has been postulated that the prevalence of polycystic ovary syndrome (PCOS) in female-to-male transsexuals (FMTs) is higher than normal. AIM The aim of the study was to investigate the prevalence of PCOS and hyperandrogenemia in FMTs, compared with controls. METHODS Sixty-one FMTs were evaluated using the Rotterdam 2003 criteria and(More)
INTRODUCTION The most common treatment regimen in female-to-male transsexuals is administration of short-acting testosterone esters intramuscularly every 2 weeks. AIM The aim of this study was to evaluate the effect of long-acting intramuscular testosterone undecanoate on body composition and bone mineral density during cross-sex hormone therapy in(More)
OBJECTIVE To compare high-sensitivity C-reactive protein (hs-CRP) with CRP as a soluble serum marker for the diagnosis of women with endometriosis. DESIGN Prospective nonrandomized controlled trial (Canadian Task Force classification II-1). SETTING University hospital. PATIENT(S) Eighty-two women were laparoscopically evaluated. No endometriosis was(More)
BACKGROUND Approximately 20% of women in Germany are smokers, and some of them are unable to stop smoking during pregnancy. As cigarette smoke generates free radicals, it has been suggested that it may be one of the major sources of oxidant stress in pregnant women and unborn fetuses. On the other hand, the human placenta is known to be a major source of(More)