Rakeshwar Bandichhor

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It is demonstrated that single-molecule tracking of a fluorescently labeled protein undergoing transient binding to model membranes presents a useful method of obtaining fluid properties. The labeled ACBP protein was tracked during its binding to free-standing giant unilamellar vesicles (GUVs) and supported bilayers prepared from the GUVs in the same(More)
The development of a practical and scalable process for the asymmetric synthesis of sitagliptin is reported. Density functional theory calculations reveal that two noncovalent interactions are responsible for the high diastereoselection. The first is an intramolecular hydrogen bond between the enamide NH and the boryl mesylate S═O, consistent with MsOH(More)
The title compound (CDC II), C28H28N6O3, is a potential impurity found in commercial product candesartan cilexetil, consist of N-ethylation of tetrazole moiety attached to biphenyl ring, selectively at N-6 position. The Crystal structure held together by CHO intermolecular interactions. Crystal structure of the title compound was obtained by single(More)
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