Rakesh Jain

Learn More
BACKGROUND Attention-deficit/hyperactivity disorder (ADHD) is a common neurobehavioral psychiatric disorder that afflicts children, with a reported prevalence of 2.4% to 19.8% worldwide. Stimulants (methylphenidate [MPH] and amphetamine) are considered first-line ADHD pharmacotherapy. MPH is a catecholamine reuptake inhibitor, whereas amphetamines have(More)
INTRODUCTION Lisdexamfetamine dimesylate (LDX) is a long-acting prodrug stimulant for the treatment of attention-deficit/hyperactivity disorder (ADHD). Post hoc subgroup analyses were performed from two studies in children with ADHD to compare the efficacy of LDX in participants who had received prior methylphenidate (MPH) treatment with that of the overall(More)
  • Shujie Dong, Paulo Delucca, R. Jason Geijskes, John Ke, Kristin Mayo, Pearl Mai +9 others
  • 2013
The sugarcane plant, with complex genetic characteristics and a lengthy breeding process, is challenging for genetic improvement through traditional breeding. Genetic engineering offers an opportunity for trait-specific sugarcane variety improvement. Transformation and transgene expression are key technologies to enable the application of biotechnology to(More)
Reliability-based robust design optimization (RBRDO) is one of the most important tools developed in recent years to improve both quality and reliability of the products at an early design stage. This paper presents a comparative study of different formulation approaches of RBRDO models and their performances. The paper also proposes an evolutionary(More)