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  • Rajnish A. Gupta, J Tan, +4 authors Raymond N. Dubois
  • Biology, Medicine
  • Proceedings of the National Academy of Sciences…
  • 2000 (First Publication: 21 November 2000)
  • There is evidence from both genetic and pharmacologic studies to suggest that the cyclooxygenase-2 (COX-2) enzyme plays a causal role in the development of colorectal cancer. However, little is knownExpand
  • Rajnish A. Gupta, Jeffrey A. Brockman, Pasha Sarraf, Timothy M. Willson, Raymond N. Dubois
  • Biology
  • The Journal of Biological Chemistry
  • 2001 (First Publication: 10 August 2001)
  • Activation of the nuclear hormone peroxisome proliferator-activated receptor γ (PPARγ) inhibits cell growth and promotes differentiation in a broad spectrum of epithelial derived tumor cell lines.Expand
  • Rajnish A. Gupta, David Brent Polk, +4 authors Richard M Peek
  • Biology
  • The Journal of Biological Chemistry
  • 2001 (First Publication: 17 August 2001)
  • Helicobacter pylori colonization leads to epithelial cell hyperproliferation within inflamed mucosa, but levels of apoptosis vary, suggesting that imbalances between rates of cell production and lossExpand