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Barley, globally the fourth most important cereal, provides food and beverages for humans and feed for animal husbandry. Maximizing grain yield under varying climate conditions largely depends on the optimal timing of flowering. Therefore, regulation of flowering time is of extraordinary importance to meet future food and feed demands. We developed the(More)
In this paper, we present a method of testing digital circuits during normal operation. The resources used to perform on-line testing are those which are inserted to alleviate the off-line testing problem. The off-line testing resources are modified such that during system operation they can also observe the normal inputs and outputs of a combinational(More)
Editing of the human genome to correct disease-causing mutations is a promising approach for the treatment of genetic disorders. Genome editing improves on simple gene-replacement strategies by effecting in situ correction of a mutant gene, thus restoring normal gene function under the control of endogenous regulatory elements and reducing risks associated(More)
Genome-wide association studies (GWAS) based on linkage disequilibrium (LD) provide a promising tool for the detection and fine mapping of quantitative trait loci (QTL) underlying complex agronomic traits. In this study we explored the genetic basis of variation for the traits heading date, plant height, thousand grain weight, starch content and crude(More)
  • Philip G Janicak, Sheila M Dowd, Brian Martis, Danesh Alam, Dennis Beedle, Jack Krasuski +4 others
  • 2002
BACKGROUND Many severely depressed patients do not benefit from or tolerate existing treatments. Repetitive transcranial magnetic stimulation (rTMS) has been reported to benefit depression. We compared rTMS to electroconvulsive therapy (ECT) in severely ill, depressed patients. METHODS Twenty-five patients with a major depression (unipolar or bipolar)(More)
Non-host resistance, NHR, to non-adapted pathogens and quantitative host resistance, QR, confer durable protection to plants and are important for securing yield in a longer perspective. However, a more targeted exploitation of the trait usually possessing a complex mode of inheritance by many quantitative trait loci, QTLs, will require a better(More)
  • Alessandro Tondelli, Xin Xu, Marc Moragues, Rajiv Sharma, Florian Schnaithmann, Christina Ingvardsen +32 others
  • 2013
Two hundred sixteen barley (Hordeum vulgare L.) cultivars were selected to represent the diversity and history of European spring two-row barley breeding and to search for alleles controlling agronomic traits by association genetics. The germplasm was genotyped with 7864 gene-based single nucleotide polymorphism markers and corresponding field trial trait(More)
Heading time is a complex trait, and natural variation in photoperiod responses is a major factor controlling time to heading, adaptation and grain yield. In barley, previous heading time studies have been mainly conducted under field conditions to measure total days to heading. We followed a novel approach and studied the natural variation of time to(More)
This research evaluated the genotypic variation in a diverse set of 233 barley genotypes including 57 landraces in the context of early drought tolerance using polyethylene glycol-(PEG) induced osmotic stress on germinating seeds. The effect of PEG treatment ranged from accelerating to delaying the germination rate. PEG showed inhibitory effects on all(More)