Rajeshwar Prasad Sinha

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Increases in ultraviolet radiation at the Earth's surface due to the depletion of the stratospheric ozone layer have recently fuelled interest in the mechanisms of various effects it might have on organisms. DNA is certainly one of the key targets for UV-induced damage in a variety of organisms ranging from bacteria to humans. UV radiation induces two of(More)
Cyanobacteria are primitive photosynthetic oxygen-evolving prokaryotes that appeared on the Earth when there was no ozone layer to protect them from damaging ultraviolet radiation (UVR). UVR has both direct and indirect effects on the cyanobacteria due to absorption by biomolecules and UVR-induced oxidative stress, respectively. However, these organisms(More)
DNA is one of the prime molecules, and its stability is of utmost importance for proper functioning and existence of all living systems. Genotoxic chemicals and radiations exert adverse effects on genome stability. Ultraviolet radiation (UVR) (mainly UV-B: 280-315 nm) is one of the powerful agents that can alter the normal state of life by inducing a(More)
We have screened two Nostoc species inhabiting diverse habitats for the presence of sunscreening mycosporine-like amino acid (MAA) compounds. The identification and characterization of one MAA (RT 3.1–3.8 min, λmax −334 nm) from both Nostoc species were performed using absorption spectroscopy, high-performance liquid chromatography (HPLC), electrospray(More)
In vivo chlorophyll fluorescence analysis reflecting the photosystem II functionality was investigated in the cyanobacterium Anabaena variabilis PCC 7937 under simulated solar radiation in a combination with various cut-off filters (WG 280, WG 295, WG 305, WG 320, WG 335, WG 345, and GG 400) to assess the effects of photosynthetically active radiation(More)
The adaptability of cyanobacteria in diverse habitats is an important factor to withstand harsh conditions. In the present investigation, the impacts of photosynthetically active radiation (PAR; 400–700 nm), ultraviolet-B (UV-B; 280–315 nm), and PAR + UV-B radiations on two cyanobacteria viz., Nostoc sp. HKAR-2 and Nostoc sp. HKAR-11 inhabiting diverse(More)
  • Vinod K Richa, Minu Kannaujiya, Garvita Kesheri, Rajeshwar P Singh, Sinha, Rajeshwar P Sinha
  • 2013
Phycobiliproteins (PBPs) are a group of antennae-protein pigments involved in light-harvesting in cyanobacteria, rhodophytes, cryptomonads and cyanelles. The phycobiliproteins are organized in supramolecular complexes, called phycobilisomes (PBSs), which are assembled in regular arrays on the outer surface of the thylakoid membrane. They have antimicrobial,(More)
Cyanobacteria are known to biosynthesize mycosporine-like amino acids (MAAs) as photoprotective compounds against ultraviolet radiation. Anabaena sp., isolated from the hot springs of Rajgir, India, produces a single MAA shinorine (retention time = 2.2 min and absorption maximum at 334 nm) as purified by high-performance liquid chromatography. The MAA(More)
We studied the temporal generation of reactive oxygen species (ROS) in the cyanobacterium Anabaena variabilis PCC 7937 under simulated solar radiation using WG 280, WG 295, WG 305, WG 320, WG 335, WG 345, and GG 400 nm cut-off filters to find out the minimum exposure time and most effective region of the solar spectrum inducing highest level of ROS. There(More)
Peroxide scavenging potential of ultraviolet-B-absorbing mycosporine-like amino acids isolated from a marine red alga Bryocladia sp. Ultraviolet-B (UV-B; 280–315 nm)-absorbing mycosporine-like amino acids (MAAs) were extracted and purified from a marine red alga Bryocladia sp. by using high performance liquid chromatography. We have detected four MAAs(More)