Rajashree Patnaik

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Insecticides and their residues are known to cause several types of ailments in human body. An attempt had been made to assess digitally the geno-toxicity of methyl parathion (MP) and chlorpyrifos (CP) to in vitro-grown HepG2 cell line, with Hoechst 33342 staining, comet, and micronucleus assays. Additionally, "acridine orange/ethidium bromide" (AO/EB)(More)
The present study examines the toxicity of HgCl2, using in vitro grown lymphocytes from human umbilical cord blood. Lymphocytes were diluted with Dulbecco’s modified Eagle’s medium, and were grown in the presence of grading doses of HgCl2. The cell-toxicity on grown lymphocytes was assessed using three staining procedures, trypan blue (TB) assay, acridine(More)
OBJECTIVES To locate a plant with suitable phytochemicals for use as antimicrobial agents to control multidrug-resistant (MDR) bacteria as a complementary medicine, without host toxicity as monitored through cultured lymphocytes from human umbilical cord blood. METHODS The methanol crude leaf extract of the plant Woodfordia fruticosa was subjected to(More)
This work describes that cytotoxicity of lead chloride and lead acetate to in vitro cultured lymphocytes from human umbilical cord blood, using four monitoring methods namely, trypan blue staining, acridine orange/ethidium bromide staining, 3-[4,5-dimethylthiazol-2-yl] 2,5-diphenyl tetrazolium bromide (MTT) and neutral red uptake assays; lead genotoxicity(More)
The aim was to investigate whether a human neural stem cell (NSC) line derived from human umbilical cord blood (hUCB) can be used for toxicity study. Toxicity of both neurotoxic environmental xenobiotics, methyl mercury chloride (CH3HgCl), lead acetate (CH3COOPb), and chlorpyrifos (CP), and non-neurotoxic insecticide, dichlorvos, as well as non-neurotoxic(More)
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