Learn More
BACKGROUND Single-step EUS-guided transmural drainage of pseudocysts has been reported, but there are no published prospective studies on clinical outcomes. OBJECTIVE To assess the safety and the efficacy of single-step EUS-guided placement of large endoprostheses to treat simple and complicated pseudocysts. DESIGN Prospective cohort study. SETTING(More)
BACKGROUND AND STUDY AIMS The accurate diagnosis of indeterminate pancreaticobiliary strictures presents a clinical dilemma. Probe-based confocal laser endomicroscopy (pCLE) offers real-time in vivo microscopic tissue examination that may increase sensitivity for the detection of malignancy. the objective of this study was to develop and validate a standard(More)
BACKGROUND Because of the low sensitivity of current ERCP-guided tissue sampling methods, management of patients with indeterminate pancreaticobiliary strictures is a challenge. Probe-based confocal laser endomicroscopy (pCLE) enables real-time microscopic visualization of strictures during an ongoing ERCP. OBJECTIVE To document the utility, performance,(More)
NBI and MBI may enhance the diagnosis and characterization of mucosal lesions in the GI tract, particularly as adjunctive techniques to magnification endoscopy. Standardization of image characterization, further image-to-pathology correlation and validation, and the impact of these technologies on patient outcomes are necessary before endorsing the use of(More)
OBJECTIVE We tested the hypothesis that impaired kidney function in the elderly is associated with a more rapid rate of cognitive decline. METHODS Baseline serum was used to calculate estimated glomerular filtration rate (eGFR), using the Modification of Diet in Renal Disease formula, for 886 elderly without dementia participating in the Rush Memory and(More)
BACKGROUND & AIMS Plastic stents, placed via endoscopy to drain pancreatic fluid collections (PFCs), require repeat access. Covered metal stents are larger in diameter and can be inserted in a single step, but can migrate. We evaluated the safety and efficacy of a lumen-apposing, covered, self-expanding metal stent (LACSEMS) for PFC drainage. METHODS We(More)
BACKGROUND The purpose of this study was to determine the incidence and outcome of pancreaticobiliary and duodenal (PB/D) perforations from periampullary endoscopic procedures and to examine whether clinical indexes are predictive of the need for operative management. METHODS A retrospective review compared patients who had operative intervention for PB/D(More)
To promote the appropriate use of new or emerging endoscopic technologies and those technologies that have an impact on endoscopic practice, the ASGE Technology Committee presents relevant information to practicing physicians in the form of technology reviews. Evidence-based methodology is employed wherein a MEDLINE literature search is performed to(More)
OBJECTIVES This study compared p53 expression with B7-H4, a novel cancer biomarker, in pancreatic ductal adenocarcinoma (PDA) resection specimens and in a pilot series of endoscopic ultrasound-guided fine-needle aspirations (EUS-FNAs). METHODS B7-H4 and p53 expression were evaluated by immunoperoxidase methods in 36 PDA and 15 EUS-FNA specimens and were(More)