Raj Bhushan Singh

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Curcumin, a constituent of the spice turmeric, has been shown to reduce the adenoma burden in rodent models of colorectal cancer accompanied by a reduction of levels of the oxidative DNA adduct 3-(2-deoxy-beta-di-erythro-pentafuranosyl)-pyr[1,2-alpha]-purin-10(3H)one (M(1)G) and of expression of the enzyme cyclooxygenase-2 (COX-2). We tested the hypothesis(More)
Worldwide, most patients with asthma are treated in primary care. Optimal primary care management of asthma is therefore of considerable importance. This IPCRG Guideline paper on the management of asthma in primary care is fully consistent with GINA guidelines. It is split into two sections, the first on the management of adults and schoolchildren, and the(More)
BACKGROUND There are very few community-based studies on the prevalence of asthma in Indian children. We aimed to estimate the prevalence of asthma in children under 12 years of age and to study possible differences in the prevalence of childhood asthma in urban and rural areas of Tamil Nadu. METHODS A total of 584 children from Chennai and 271 children(More)
Curcumin, a constituent of the spice turmeric, has been shown to reduce the adenoma burden in rodent models of colorectal cancer accompanied by a reduction of levels of the oxidative DNA adduct 3-(2-deoxy-h-di-erythro-pentafuranosyl)-pyr[1,2-A]-purin-10(3H)one (M1G) and of expression of the enzyme cyclooxygenase-2 (COX-2). We tested the hypothesis that(More)
OBJECTIVE In India, 50%-80% of patients with tuberculosis (TB) seek private care. This study set out to explore HIV testing and referral practices of private hospital doctors treating patients with TB. METHODS Interviews were conducted with private hospital doctors (n = 15). Interviews covered HIV testing, linking HIV-positive patients with TB to HIV(More)
INTRODUCTION Despite efforts to improve the management of asthma worldwide, few options exist for evaluating the specific needs or the success of these activities in a manner free from bias. OBJECTIVES To examine the management of asthma exacerbations by physicians using standardized audiovisual presentations of asthma. METHODS Practitioners (n = 70) in(More)
All the heterocyclic compounds are of great interest in Pharmaceutical Chemistry. Out of these heterocyclic compounds the benzfused heterocyclic compound, i.e. benzimidazole is an important pharmacophore and privileged structure in medicinal chemistry. Recently many benzimidazole drugs like antiparasitic, thiabendazole, mebendazole and albendazole,(More)
A 69-year-old man presented with sudden onset of macroscopic hematuria. While an ultrasound of the bladder revealed a posterior bladder mass, subsequent flexible cystoscopy demonstrated only an area of irregular urothelium. Initial general anesthetic cytoscopy and biopsy revealed conventional G2/3 T1 TCC. Histology of a further formal resection of this(More)
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