Rainer Müller

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We discuss the problem of capturing media streams which occur during a live lecture in class or during a telepresentation. Instead of presenting yet another method or system for capturing the classroom experience, we introduce some informal guidelines and show their importance for such a system. We derive from these guidelines a formal framework for sets of(More)
Phosphoinositides serve crucial roles in cell physiology, ranging from cell signalling to membrane traffic. Among the seven eukaryotic phosphoinositides the best studied species is phosphatidylinositol-4,5-bisphosphate (PI(4,5)P2), which is concentrated at the plasma membrane where, among other functions, it is required for the nucleation of endocytic(More)
The endeavour to perform tailored chemical reactions in the challenging environment of the intact cell delves deeply into the biological sciences. Requirements include strict bioorthogonality of the reactants and reactions that occur spontaneously and quickly in an aqueous environment or at the interface of membranes. Commonly used reactions that meet these(More)
Automatic recording and capturing of live lectures and presentations has been explored and evaluated by various research projects since the mid 90s and has meanwhile been adapted by a number of commercial systems. Here, we discuss and summarize “Authoring on the Fly” (AOF) which is a special incarnation of this idea. The purpose of this paper is to give an(More)
In order to improve the acceptance of recorded presentations, we introduce a new open document type covering a wide range of different media classes typically appearing in this scenario. Instances of this document type can be replayed using our time-based synchronization model. Random access in combination with the realized stream/media-layered(More)
Phosphatidylinositol 3-phosphate (PtdIns(3)P) is a phospholipid residing on early endosomes, where it is proposed to be involved in endosomal fusion. We synthesized membrane-permeant derivatives of PtdIns(3)P, including a caged version that is to our knowledge the first photoactivatable phosphoinositide derivative developed so far. In living cells,(More)
In the presentation recording scenario there are two aspects regarding the user interface: How the recording is done (i.e., how the presenter or his/her assistants have to interact with the recording tools (hardware and software)), and how users can access the produced multimedia documents (i.e., how replay, as well as search and navigation in the files can(More)