Rainer Bader

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Dislocation remains a serious complication of total hip replacement. An insufficient range of motion can lead to impingement of the prosthetic neck on the acetabular cup. Together with the initiation of subluxation and dislocation, recurrent impingement can cause material failure in the liner. The objective of this study was to generate a validated finite(More)
We present a case involving the revision of a total knee arthroplasty with a metal femoral component using a ceramic implant due to metal hypersensitivity. A 58-year-old female patient underwent total knee arthroplasty (TKA) with a standard metal bicondylar knee system. She suffered from persistent pain and strong limitations in her range of motion (ROM)(More)
The binding of 125I-von Willebrand factor (125I-vWF) to platelets stimulated by thrombin, ADP, and a combination of ADP + epinephrine (EPI) is specific, saturable, and reversible. Active platelet metabolism and divalent cations are required for binding induced by these stimuli, but not by ristocetin, suggesting the existence of different mechanisms involved(More)
Mitogenesis, cellular aggregation, and motility follow upon the interaction of fibrinogen with certain defined cell surface receptors. In addition to circulating platelets and vascular endothelium, monocytes express what appears to be a receptor for fibrinogen. Evidence is presented here that the leukocyte adhesion receptor Mac-1 can be specifically induced(More)
Introduction: For the reconstruction of acetabular bone defects different types of acetabular reinforcement rings are being used. In clinical practice, these implants showed to some extent good long-term results. In the present work pitfalls and complications after the implantation of acetabular reinforcement rings as well as possible solutions are being(More)
Platelet activation altered the binding of three monoclonal antibodies (monovalent Fab' fragment) directed against the glycoprotein (GP) IIb/IIIa complex. An increased binding of two- to threefold occurred after stimulation with thrombin or phorbol myristate acetate (PMA), with slight but significant increase in the dissociation constants (Kd) of two(More)
Dislocation of the artificial joint is a serious complication of total hip replacement. Various factors with an influence on dislocation stability were determined clinically. Our goal was to develop a method for evaluating experimentally the parameters implant design, position and the load situation for their influence on joint stability. With the newly(More)
The success and long-term survival rates of modern joint arthroplasty leads to a high patient satisfaction and, together with its technical improvements, has broadened the indications to an increasingly younger population. Limitations to the established systems are the long-term survival rates, which are mainly influenced by wear of the articulating parts(More)
Possible causes for failure of total knee endoprostheses represent wear, malpositioning, maldimensioning and inadequate design of the implant components, manufacturing defects, material fatigue, corrosion, overloading, infection, and allergy against implant materials. There is a broad spectrum of methodical approaches for the analysis of failure cases.(More)
Implant infections remain feared and severe complications after total joint arthroplasty. The incidence of multi-resistant pathogens, causing such infections, is rising continuously, and orthopaedic surgeons are confronted with an ever-changing resistance pattern. Anti-infectious surface coatings aim for a high local effective concentration and a low(More)