Raik Niemann

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The interaction of human serum high density lipoproteins (HDL) with mouse peritoneal macrophages and human blood monocytes was studied. Saturation curves for binding of apolipoprotein E-free [125I]HDL3 showed at least two components: non-specific binding and specific binding that saturated at approximately 40 micrograms HDL protein/ml. Scatchard analysis of(More)
The effects of the slow Ca++ channel blocker, nifedipine, and ACAT inhibitor, octimibate, on the cholesterol metabolism of cholesterol-loaded macrophages were compared. We demonstrated that apolipoprotein A-I containing high density lipoproteins (HDL) bind to specific receptor sites on macrophages, are internalized, take up cholesterol, and are then(More)
The efficient execution of multi-criteria queries has gained increasing interest over the last years. In the present paper we propose an R-tree based approach for queries addressing textual as well as geographic filter conditions. Whereas most previous approaches use an index structure optimised for a single criterion adding special treatment for the other(More)
FAM40B (STRIP2) is a member of the striatin-interacting phosphatase and kinase (STRIPAK) complex that is involved in the regulation of various processes such as cell proliferation and differentiation. Its role for differentiation processes in embryonic stem cells (ESCs) is till now completely unknown. Short hairpin RNA (shRNA)-mediated silencing of Fam40b(More)
Nowadays developers and end users of data management systems are challenged with the reduction of the "energy consumption footprint" of existing implementations and configurations. In other words, the energy efficiency has to be optimized, either by increasing the performance or by consuming less resources. In fact, there is a big number of factors that(More)
  • Raik Niemann
  • 2015
In the last couple of years it became more difficult for end users of data management system to optimize existing systems for performance and energy consumption. The reasons are the big number of data management systems to chose from, extensive use cases and a variety of hardware configurations. The number of factors that influence the performance and(More)
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