Rahul Lokhande

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Emergence of multidrug-resistant tuberculosis (MDR-TB) has been a cause of concern in both developed and developing countries. Hence, there is a need for continuous monitoring of drug resistance to anti-tuberculosis drugs in tuberculosis patients. A study was conducted to determine the prevalence anti-TB drug resistance in Mycobacterium tuberculosis(More)
BACKGROUND Diabetes mellitus (DM) increases tuberculosis (TB) risk, and there is increasing concern over the public health implications of the convergence of these two epidemics. Screening for TB among people with DM is now recommended in India. METHODS People with DM seeking care at a large public sector tertiary care hospital clinic in Pune, India, were(More)
The present study was undertaken to detect Pneumocystis jirovecii infection among HIV-positive patients presenting with symptoms of lower respiratory tract infection and analyze the associated dihydropteroate synthase (DHPS) and dihydrofolate reductase (DHFR) mutations. P. jirovecii infection was detected in 12.6 % cases. We did not find DHPS gene mutations(More)
INTRODUCTION Tuberculosis disease (TB) remains an important global health threat. An evidence-based response, tailored to local disease epidemiology in high-burden countries, is key to controlling the global TB epidemic. Reliable surrogate biomarkers that predict key active disease and latent TB infection outcomes are vital to advancing clinical research(More)
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