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Sleep EEG in the sigma and delta frequency bands was subjected to spectral analysis in 8 normal young adults. In each subject, power density of sigma and delta oscillated reciprocally during NREM sleep, confirming an observation made initially with period/amplitude analysis. In REM sleep, power density for both frequency bands was at its lowest levels.(More)
In longitudinal data with correlated errors, we apply the likelihood and residual likelihood approaches to obtain the corrected Akaike information criterion (AICc) and the residual information criterion (RIC), respectively. Simulation studies show that AICc outperforms the Akaike information criterion (AIC) when the numbers of subjects and repeated(More)
CONTEXT Direct-to-consumer (DTC) advertising of prescription drugs in the United States is both ubiquitous and controversial. Critics charge that it leads to overprescribing, while proponents counter that it helps avert underuse of effective treatments, especially for conditions that are poorly recognized or stigmatized. OBJECTIVE To ascertain the effects(More)
OBJECTIVES We estimated the prevalence and longitudinal correlates of use of complementary and alternative medicine (CAM) at midlife among participants of the Study of Women's Health Across the Nation (SWAN). METHODS Multiple logistic regression was used to evaluate the relationship between baseline survey-reported symptoms and use of herbal, spiritual,(More)
BACKGROUND The objective of this study was to understand the attitudes and preferences of risk-eligible women regarding use of tamoxifen for breast cancer risk reduction. METHODS A cross-sectional, mixed-methods interview study was conducted at a university medical center and at community sites. Participants were women who had an estimated 5-year breast(More)
BACKGROUND Patients communicate their desires and expectations largely by making requests. However, the antecedents and consequences of request fulfillment have received limited attention. OBJECTIVE To describe patient and physician characteristics associated with request fulfillment and to understand the consequences of request fulfillment and(More)
BACKGROUND The importance of recruiting and retaining women from diverse populations is well recognized; however, the recruitment process often presents greater challenges at higher costs than initially anticipated. OBJECTIVES To describe recruitment strategies and costs from a study evaluating women's preferences regarding tamoxifen use for primary(More)
Prenatal environmental exposures are among the risk factors being explored for associations with autism. We applied a new procedure combining multiple scan cluster detection tests to identify geographically defined areas of increased autism incidence. This procedure can serve as a first hypothesis-generating step aimed at localized environmental exposures,(More)
BACKGROUND Many patients with upper gastrointestinal (GI) bleeding have a benign outcome and could receive less intensive and costly care if accurately identified. We sought to determine whether early endoscopy performed shortly after admission in the emergency department could significantly reduce the health care use and costs of caring for patients with(More)