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Methicillin resistant Staphylococcus aureus (MRSA) comprised about 7.5% per annum of all S. aureus isolated in a general hospital in Jeddah, Saudi Arabia during the 3 year period 1990-1992. Most isolates were from wound sites (71%). Resistance to gentamicin (83%) and tetracycline (93%) was frequently observed whilst resistance to ciprofloxacin (1%) and(More)
Zingiber officinale (ZO), commonly known as ginger, has been traditionally used in the treatment of diabetes mellitus. Several studies have reported the hypoglycaemic properties of ginger in animal models. The present study evaluated the antihyperglycaemic effect of its aqueous extract administered orally (daily) in three different doses (100, 300, 500(More)
The epidemiology of mycobacterial infections was studied in a wide cross-section of the Jeddah population over 2 years (1987-1989). Saudis, non-Saudis and patients from a stable population attending National Guard King Khalid Hospital (NGKKH) were compared. The ratio of Saudi to non-Saudi was 1:2 and males accounted for 65% of the total. The incidence was(More)
  • R Zaman
  • 1992
A 12-month survey on the incidence of campylobacter infection in 1217 patients with diarrhoea was carried out in Jeddah, Saudi Arabia. Campylobacters were isolated from 55 (4.5%) patients, second in prevalence to salmonellas (6.2%). Shigellas were isolated from 4.2% of patients. Campylobacter isolation rates were high in children of all ages, as well as in(More)
We report the absence of superoxide dismutase (SOD-1) gene mutations in 30 patients with amyotrophic lateral sclerosis (ALS) including individuals with a confirmed family history of ALS (familial ALS/FALS), ALS with an unclear family history (UFALS) and sporadic ALS (SALS). Single strand conformation polymorphism (SSCP) and sequence analysis of the 5 SOD-1(More)
Resistance to six anti-mycobacterial agents rifampicin, isoniazid, streptomycin, ethambutol, p-amino salicylic acid and cycloserine was studied. Variations in the resistance pattern among Saudi, non-Saudi and a stable National Guard King Khalid Hospital (NGKKH) population were investigated. A high percentage of relapse cases, 21%, was recorded. Among the(More)
Over the last few decades proteins and peptide therapeutics have occupied an enormous fraction of pharmaceutical industry. Despite their high potential as therapeutics, the big challenge often encountered is the effective administration and bioavailability of protein therapeutics in vivo system. Peptide molecules are well known for their in vivo short(More)
All isolates of Pseudomonas aeruginosa in our laboratory from hospitalised patients were collected over a 4-month period in 1993/94. Details of the patients including length of stay, transfer from another hospital, nationality, diagnosis and antibacterial treatment were noted. Each patient was assessed as to whether the first isolate during the study period(More)
Terconazole, a new triazole ketal, is found to be highly active in vitro on a wide range of yeasts and mycelium-forming fungi. The in vitro activity depends largely on the medium used. In vitro it is a potent antifungal agent in preventing the morphogenetic transformation of the yeast into the (pseudo-)mycelium form of Candida albicans. In vivo terconazole(More)
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