Raguraman Rajeswari

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OBJECTIVES To investigate the factors associated with delay in 1) care-seeking (patient delay), and 2) diagnosis by health providers (health system delay), among smear-positive tuberculosis patients, before large-scale DOTS implementation in South India. METHODS New smear-positive patients were interviewed using a structured questionnaire. RESULTS Among(More)
OBJECTIVE To quantify the socio-economic impact of tuberculosis on patients and their families from the costs incurred by patients in rural and urban areas. DESIGN An interview schedule prepared from 17 focus group discussions was used to collect socio-economic demographic characteristics, employment, income particulars, expenditure on illness and effects(More)
SETTING Tiruvallur District, south India. OBJECTIVES To examine gender differences in tuberculosis among adults aged >14 years with respect to infection and disease prevalence, health care service access, care seeking behaviour, diagnostic delay, convenience of directly observed treatment (DOT), stigma and treatment adherence. METHODS Data were(More)
Tuberculosis (TB) often leaves its impact physically, socially and mentally on patients. The goal of current tuberculosis services is microbiological cure of tuberculosis. Understanding patients' perceptions about TB will enable better design of a client-oriented comprehensive programme for tuberculosis. We interviewed patients registered for treatment(More)
BACKGROUND Health-related quality of life (HRQoL) measures the impact of a disease by assessing the health status of patients. OBJECTIVE To assess the HRQoL of tuberculosis (TB) patients one year after treatment completion. METHODS Patients registered under the TB control programme from July 2002 to June 2003 in a TB Unit in south India were interviewed(More)
BACKGROUND In Tiruvallur District, South India, tuberculosis cases are detected at health facilities (HF) as part of a DOTS programme, and by screening adults through community survey (CS) as part of ongoing epidemiological research. OBJECTIVE To compare socio-demographic, clinical and bacteriological characteristics and treatment outcomes of all patients(More)
Electrospraying of hydroxyapatite (HA) nanoparticles onto the surface of polymer nanofibers provides a potentially novel substrate for the adhesion, proliferation and differentiation of mesenchymal stem cells (MSCs) into bone tissue regeneration. HA nanoparticles (4%) were electrosprayed on the surface of electrospun polycaprolactone (PCL) nanofibers (420 ±(More)
AIM To assess the effect of diabetes on tuberculosis (TB) treatment outcome and sputum conversion among new smear-positive (NSP) cases registered under Directly Observed Treatment Short Course in South India. METHODS Details on sputum conversion and TB treatment outcome were collected from case records of NSP cases (N = 332; M/F 247:85) registered at TB(More)
OBJECTIVE To delineate the course of serum neopterin (s-neo) concentrations in patients with pulmonary tuberculosis who are on anti-tuberculosis therapy. DESIGN S-neo concentrations were measured by high performance liquid chromatography (HPLC) in 39 patients treated for pulmonary tuberculosis at pretreatment, at one month and at end of treatment. It was(More)
OBJECTIVE The efficacy of a short-course regimen in the treatment of brain tuberculoma and computerised tomography (CT) scan appearance before, during and after antituberculosis treatment was studied in a controlled clinical trial. DESIGN Patients aged over 5 years with tuberculoma of the brain diagnosed by CT scan were randomly allocated to one of the(More)