Raghavendra K. Guru

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UNLABELLED We have developed a web-based system (Pathway Miner) for visualizing gene expression profiles in the context of biological pathways. Pathway Miner catalogs genes based on their role in metabolic, cellular and regulatory pathways. A Fisher exact test is provided as an option to rank pathways. The genes are mapped onto pathways and gene product(More)
Pseudomonas (PI2) capable of degrading pyridine was isolated from the mixed population of the activated sludge unit which was being used for treating complex effluents, the strain was characterized. Aerobic degradation of pyridine was studied with the isolated strain and the growth parameters were evaluated. Pyridine degradation was further conformed by(More)
Eosinophils are one of the target cells in anti-inflammatory drug therapy that may contribute to variable responsiveness as a result of differences in intracellular signaling pathways controlling apoptosis. However, little is known about eosinophil transcriptome differences between individuals, due in part to the difficulty in obtaining sufficient(More)
CONTEXT Boswellic acid consists of a series of pentacyclic triterpene molecules that are produced by the plant Boswellia serrata. The potential applications of Bowsellic acid for treatment of cancer have been focused here. AIMS To predict the property of the bowsellic acid derivatives as anticancer compounds by various computational approaches. (More)
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