Rafe M. Brown

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Depletion of dopamine in a circumscribed area of association cortex in rhesus monkeys produces an impairment in spatial delayed alternation performance nearly as severe as that caused by surgical ablation of the same area. This behavioral deficit can be pharmacologically reversed with dopamine agonists such as L-dopa and apomorphine. These data provide(More)
Endogenous monoamine concentrations and turnover rates vary markedly in different regions of neocortex as well as in various subcortical structures of young adult rhesus monkeys. Monoamine levels and synthesis rates in amygdala, hippocampus, neostriatum, thalamus and brain stem are generally similar to comparable measures previously reported in a variety of(More)
Ranidae is a large anuran group with a nearly cosmopolitan distribution. We investigated the phylogenetic relationships and early biogeographic history of ranid frogs, using 104 representatives of all subfamilies and families, sampled from throughout their distribution. Analyses of approximately 1570 bp of nuclear gene fragments (Rag-1, rhod, Tyr) and(More)
The interface of the Asian and Australian faunal zones is defined by a network of deep ocean trenches that separate intervening islands of the Philippines and Wallacea (Sulawesi, the Lesser Sundas, and the Moluccas). Studies of this region by Wallace marked the genesis of the field of biogeography, yet few workers have used molecular methods to investigate(More)
We review the taxonomic status of Philippine bent-toed geckos previously referred to Cyrtodactylus agusanensis. We delineate four evolutionary lineages within the C. agusanensis complex from the southeastern islands of the archipelago and describe three of these lineages as new species. The new species and true C. agusanensis are identified by numerous,(More)
The spectacular, virtually endemic radiation of Philippine semi-fossorial skinks of the genus Brachymeles represent one of the few radiations of scincid lizards to possess both fully limbed and limbless species. And yet, nothing is known of the phylogenetic relationships of this exceptional group. Morphologically similar body plans have made it difficult to(More)
In the Philippines, Pleistocene sea level oscillations repeatedly connected and isolated neighboring islands. Hence, an understanding of the island platforms adjoined during periods of low sea level has led biologists to a suite of expectations that, taken together, represent a paradigm for the process of recent diversification in southeast Asia. We employ(More)
Skinks of the genus Sphenomorphus are the most diverse clade of squamates in the Philippine Archipelago. Morphological examination of these species has defined six phenotypic groups that are commonly used in characterizations of taxonomic hypotheses. We used a molecular phylogeny based on four mitochondrial and two nuclear genes to assess the group’s(More)
We review the Philippine frogs of the genus Leptobrachuim. All previous treatments have referred Philippine populations to L. hasseltii, a species we restrict to Java and Bali, Indonesia. We use external morphology, body proportions, color pattern, advertisement calls, and phylogenetic analysis of molecular sequence data to show that Philippine populations(More)
– We describe a new species of Luperosaurus from the Sierra Madre Mountain Range of northern Luzon Island, Philippines. Luperosaurus kubli, new species, is distinguished from all Philippine Luperosaurus by the combination of its large body size (105.4 mm for the holotype), reduced interdigital webbing, cutaneous expansions on limbs limited to only the(More)