Rafaela Xavier

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Few concepts in recent years have garnered more disease research attention than that of the intestinal (i.e. 'gut') microbiome. This emerging interest has included investigations of the microbiome's role in the pathogenesis of a variety of autoimmune disorders, including type 1 diabetes (T1D). Indeed, a growing number of recent studies of patients with T1D(More)
Background Leptospirosis is a globally disseminated zoonosis, recognized as a re-emergent neglected disease [1] and the causative pathogens are spirochetes from genus Leptospira [2]. In Brazil, more than 100.00 leptospirosis cases are reported annually, with outbreaks emerging especially during floods [3]. The microscopic agglutination test (MAT) is(More)
Toxic epidermal necrolysis (TEN), or Lyell's syndrome, is a rare cutaneous reaction, most often drug related with drugs such as sulfonamides, non-steroidal anti-inflammatory drugs, anti-convulsants and allopurinol. It is characterised by extensive mucocutaneous detachment and usually associated with severe constitutional symptoms. The mortality rate is(More)
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