Rafael Villa-Angulo

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The imprints of domestication and breed development on the genomes of livestock likely differ from those of companion animals. A deep draft sequence assembly of shotgun reads from a single Hereford female and comparative sequences sampled from six additional breeds were used to develop probes to interrogate 37,470 single-nucleotide polymorphisms (SNPs) in(More)
The Bovine HapMap Consortium has generated assay panels to genotype ~30,000 single nucleotide polymorphisms (SNPs) from 501 animals sampled from 19 worldwide taurine and indicine breeds, plus two outgroup species (Anoa and Water Buffalo). Within the larger set of SNPs we targeted 101 high density regions spanning up to 7.6 Mb with an average density of(More)
This paper describes a work related to the design and implementation of a communication tool for persons with speech and hearing disabilities. This tool provides to the user a Human-Computer interface capable of the capture and recognition of gestures belonging to the Mexican Spanish Sign Alphabet. To capture the manual expressions, a data-glove constructed(More)
Genomic structural variations represent an important source of genetic variation in mammal genomes, thus, they are commonly related to phenotypic expressions. In this work, ∼ 770,000 single nucleotide polymorphism genotypes from 506 animals from 19 cattle breeds were analyzed. A simple LD-based structural variation was defined, and a genome-wide analysis(More)
The nonlinear response of p-i-n photodiodes (PIN-PDs) has become a concern for circuit designers implementing PIN-PD-based switches because this response can significantly compromise systems performance. A major challenge with this implementation is the selection of an appropriate linear operation range from the I-V curve of the PIN-PD to reduce nonlinear(More)
Recently, for copy number variation (CNV) analysis, bovine researchers have focused mainly on the use of genome-wide SNP genotyping arrays. One of the highest densities commercially available SNPchips for cattle is the Affymetrix axiom genome-wide Bos 1, which assays 648,315 informative SNPs across the whole bovine genome. Here, we describe the microarray(More)
Copy number variations (CNVs) are an important source of genomic structural variation, and can be used as markers to investigate phenotypic and economic traits. CNVs also have functional effects on gene expression and can contribute to disease susceptibility in mammals. Currently, single nucleotide polymorphism genotyping arrays (SNP chips) are the(More)
Hypoplasia and ovarian cysts are the most common ovarian pathologies in cattle. In this genome-wide study we analyzed the signal intensity of 648,315 Single Nucleotide Polymorphisms (SNPs) and identified 1338 genes differentiating cows with ovarian pathologies from healthy cows. The sample consisted of six cows presenting an ovarian pathology and six(More)
In this paper, we present an experimental method demonstrating an improvement in the resolution of optically sampled time-interleaved analog-to-digital converters (ADCs) by applying a data averaging technique. We implemented two experiments for oversampling four times the bandwidth of an analog input signal using a multichannel time-interleaved arrangement.(More)
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