• Publications
  • Influence
HLA-G 3′ Untranslated Region Polymorphisms Are Associated with Systemic Lupus Erythematosus in 2 Brazilian Populations
Objective. HLA-G has well recognized tolerogenic properties in physiological and nonphysiological conditions. The 3′ untranslated region (3′UTR) of the HLA-G gene has at least 3 polymorphic sitesExpand
  • 33
  • 3
The +3187A/G HLA-G polymorphic site is associated with polar forms and reactive reaction in leprosy
Considering that variability in immune response genes has been associated with susceptibility to leprosy and with disease severity, leprosy presents clinicopathological variants that are highlyExpand
  • 10
  • 1
Haplotype frequencies based on eight polymorphic sites at the 3' untranslated region of the HLA-G gene in individuals from two different geographical regions of Brazil.
The Brazilian population represents an admixture of native Amerindians, Portuguese settlers and Africans who were brought as slaves during the colonization period that began in the 16th century andExpand
  • 27
Association of HLA-G 3' untranslated region variants with type 1 diabetes mellitus.
Besides the well recognized association of HLA-DRB1 and DQB1 alleles with type 1 diabetes mellitus (T1D), linkage studies have identified a gene region close to the non-classical class I HLA-G geneExpand
  • 10
Identification of two new HLA-G alleles, G*01:01:03:03 and G*01:01:21, in Brazilian individuals.
Here we report two new non-classical class I HLA-G alleles found in the Brazilian population.
  • 4
BAY 41-2272 inhibits human neutrophil functions.
BAY 41-2272 is a guanylyl cyclase (GC) stimulator derived from YC-1 (3-[(5'-hydroxymethyl-2'-furyl)-1-benzyl indazole]). Previous studies by our group showed that BAY 41-2272 activates humanExpand
  • 2
Quantitative Proteomics Reveals the Dynamic Protein Landscape during Initiation of Human Th17 Cell Polarization
Summary Th17 cells contribute to the pathogenesis of inflammatory and autoimmune diseases and cancer. To reveal the Th17 cell-specific proteomic signature regulating Th17 cell differentiation andExpand
  • 8
Early Detection of Peripheral Blood Cell Signature in Children Developing β-Cell Autoimmunity at a Young Age
The appearance of type 1 diabetes (T1D)-associated autoantibodies is the first and only measurable parameter to predict progression toward T1D in genetically susceptible individuals. However,Expand
  • 3
BAY 41-2272 inhibits human T lymphocyte functions.
BAY 41-2272 increases guanosine 3', 5'-cyclic monophosphate (cGMP) levels by stimulating soluble guanylate cyclase (sGC). In this study, we evaluated the effect of BAY 41-2272 on human T lymphocyteExpand