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Sodium/Iodide Symporter Mutant V270E Causes Stunted Growth but No Cognitive Deficiency.
- Juan Pablo Nicola, A. Reyna-Neyra, +5 authors N. Carrasco
- Biology, Medicine
- The Journal of clinical endocrinology and…
- 23 July 2015
CONTEXT Iodide (I(-)), an essential constituent of the thyroid hormones, is actively accumulated in the thyroid by the Na(+)/I(-) symporter (NIS), a key plasma membrane protein encoded by the slc5a5… Expand
Deficiency in AIM2 induces inflammation and adipogenesis in white adipose tissue leading to obesity and insulin resistance
- Zhenwei Gong, X. Zhang, +9 authors Radhika H. Muzumdar
- Chemistry, Medicine
- 11 September 2019
Absent in melanoma 2 (AIM2) is a cytosolic sensor for double-stranded DNA and a tumour suppressor. Binding of double-stranded DNA to AIM2 forms the AIM2 inflammasome, leading to activation of… Expand
Epigenetic genome-wide association methylation in aging and longevity.
The aging phenotype is the result of a complex interaction between genetic, epigenetic and environmental factors. Evidence suggests that epigenetic changes (i.e., a set of reversible, heritable… Expand
Role of mitochondrial acyl-CoA dehydrogenases in the metabolism of dicarboxylic fatty acids.
- Sivakama S. Bharathi, Y. Zhang, Zhenwei Gong, Radhika H. Muzumdar, E. Goetzman
- Chemistry, Medicine
- Biochemical and biophysical research…
- 18 June 2020
Dicarboxylic fatty acids, taken as a nutritional supplement or produced endogenously via omega oxidation of monocarboxylic fatty acids, may have therapeutic potential for rare inborn errors of… Expand
Efficacy of a Novel Mitochondrial-Derived Peptide in a Porcine Model of Myocardial Ischemia/Reperfusion Injury
- T. Sharp, Zhenwei Gong, +6 authors T. Goodchild
- JACC. Basic to translational science
- 17 June 2020
Glucose Homeostasis in Newborns: An Endocrinology Perspective.
Physiologic adaptations in the postnatal period, along with gradual establishment of enteral feeding, help maintain plasma glucose concentrations in the neonatal period. The definition of normal… Expand
Paediatric diabetes care during the COVID‐19 pandemic: Lessons learned in scaling up telemedicine services
- Christine A March, Amanda Flint, +6 authors I. Libman
- Endocrinology, diabetes & metabolism
- 21 November 2020
Paediatric diabetes care relies upon a multidisciplinary approach for the education of and collaborative medical decision-making with patients and families. It involves healthcare providers, diabetes… Expand
0927 SLEEP IN SCHOOL AGED CHILDREN WITH TYPE 1 DIABETES