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Sodium/Iodide Symporter Mutant V270E Causes Stunted Growth but No Cognitive Deficiency.
CONTEXT Iodide (I(-)), an essential constituent of the thyroid hormones, is actively accumulated in the thyroid by the Na(+)/I(-) symporter (NIS), a key plasma membrane protein encoded by the slc5a5Expand
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Deficiency in AIM2 induces inflammation and adipogenesis in white adipose tissue leading to obesity and insulin resistance
Absent in melanoma 2 (AIM2) is a cytosolic sensor for double-stranded DNA and a tumour suppressor. Binding of double-stranded DNA to AIM2 forms the AIM2 inflammasome, leading to activation ofExpand
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Epigenetic genome-wide association methylation in aging and longevity.
The aging phenotype is the result of a complex interaction between genetic, epigenetic and environmental factors. Evidence suggests that epigenetic changes (i.e., a set of reversible, heritableExpand
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Role of mitochondrial acyl-CoA dehydrogenases in the metabolism of dicarboxylic fatty acids.
Dicarboxylic fatty acids, taken as a nutritional supplement or produced endogenously via omega oxidation of monocarboxylic fatty acids, may have therapeutic potential for rare inborn errors ofExpand
Efficacy of a Novel Mitochondrial-Derived Peptide in a Porcine Model of Myocardial Ischemia/Reperfusion Injury
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Glucose Homeostasis in Newborns: An Endocrinology Perspective.
Physiologic adaptations in the postnatal period, along with gradual establishment of enteral feeding, help maintain plasma glucose concentrations in the neonatal period. The definition of normalExpand
Paediatric diabetes care during the COVID‐19 pandemic: Lessons learned in scaling up telemedicine services
Paediatric diabetes care relies upon a multidisciplinary approach for the education of and collaborative medical decision-making with patients and families. It involves healthcare providers, diabetesExpand