Radha Krishna

Diego Perez-Tilve3
Timo D. Müller3
Nickki Ottaway3
Paul T. Pfluger3
Stephen C. Woods3
3Diego Perez-Tilve
3Timo D. Müller
3Nickki Ottaway
3Paul T. Pfluger
3Stephen C. Woods
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  • Kirk M. Habegger, Kerstin Stemmer, Christine Cheng, Timo D. Müller, Kristy M. Heppner, Nickki Ottaway +21 others
  • 2013
Glucagon, an essential regulator of glucose homeostasis, also modulates lipid metabolism and promotes weight loss, as reflected by the wasting observed in glucagonoma patients. Recently, coagonist peptides that include glucagon agonism have emerged as promising therapeutic candidates for the treatment of obesity and diabetes. We developed a novel stable and(More)
Although obesity rates are rapidly rising, caloric restriction remains one of the few safe therapies. Here we tested the hypothesis that obesity-associated disorders are caused by increased adipose tissue as opposed to excess dietary lipids. Fat mass (FM) of lean C57B6 mice fed a high-fat diet (HFD; FMC mice) was "clamped" to match the FM of mice maintained(More)
  • Timo D. Müller, Anne Müller, Chun-Xia Yi, Kirk M Habegger, Carola W. Meyer, Bruce D. Gaylinn +29 others
  • 2013
The G protein-coupled receptor 83 (Gpr83) is widely expressed in brain regions regulating energy metabolism. Here we report that hypothalamic expression of Gpr83 is regulated in response to nutrient availability and is decreased in obese mice compared with lean mice. In the arcuate nucleus, Gpr83 colocalizes with the ghrelin receptor (Ghsr1a) and the(More)
UNLABELLED Genetic control of root development in rice is complex and the underlying mechanisms (constitutive and adaptive) are poorly understood. Lowland and upland varieties of indica and japonica rice with contrasting root development characteristics have been crossed, mapping populations developed and a number of QTLs in different chromosomes were(More)
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