Radha Krishna

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A subdomain of the human leptin receptor encoding part of the extracellular domain (amino acids 428 to 635) was subcloned, expressed in a prokaryotic host, and purified to homogeneity, as evidenced by SDS-PAGE, with over 95% monomeric protein. The purified leptin-binding domain (LBD) exhibited the predicted beta structure, was capable of binding human,(More)
This paper presents a method for deriving Association rules by using apriori algorithm, clustering and fuzzy set concepts. Association rules of quantitative data are presented with mean and standard deviation, and with fuzzy linguistic terms. A case study was done on the commodity data to demonstrate vitality of proposed method. The statistical and fuzzy(More)
A new rhizosphere soil bacterium that exhibits antimicrobial potential against human pathogens was isolated. On the basis of 16S ribosomal RNA nucleotide sequence homology and subsequent phylogenetic tree analysis, the strain PUW5 was identified as Pseudomonas putida. A bioactive metabolite was extracted and purified using silica gel column chromatography(More)
The microbial polyketide, 2, 4-diacetylphloroglucinol (DAPG), exhibited a broad-spectrum of anti-leukemic, anti-lung, and anti-breast cancer properties. The aim of the present investigation was to study the interactive potentials of DAPG with the metastatic proteins such as MMP-2, MMP-9, and NF-κB and antiapoptotic Bcl-2 family proteins such as Bcl-2,(More)
Provision of end of life care and coping with the emotional and existential distress engendered by palliative care demands the provision of holistic support and training for palliativists. Mentoring is an effective means of meeting this need; however little is known of mentoring in palliative care and a universally accepted learning theory of mentoring(More)
Phenazine-1-carboxamide (PCN), a naturally occurring simple phenazine derivative isolated from Pseudomonas sp. strain PUP6, exhibited selective cytotoxic activity against lung (A549) and breast (MDA-MB-231) cancer cell lines in differential and dose-dependent manner compared to normal peripheral blood mononuclear cells. PCN-treated cancer cells showed the(More)
Background maintenance is a complex problem due to varying scene conditions. Typically, a single algorithm cannot handle the complex scene changes that occur in visual surveillance applications. Also complex background modelling techniques, for example mixture of Gaussians have a high computational and communication demand compared to simple techniques such(More)
In the present world of information, text classification is a more challenging process due to the larger number of training cases and feature set present in text data. One of the most difficult tasks in the text classification problem is high dimensionality of the feature space. As many real world text classifications are not modeled or too difficult to(More)
Web Usage Mining (WUM) refers to extraction of knowledge from the web log data by application of data mining techniques. WUM generally consists of Web Log Preprocessing, Web Log Knowledge Discovery and Web Log Pattern Analysis. Web Log Preprocessing is a major and complex task of WUM. Elimination of noise and irrelevant data, thereby reducing the burden on(More)