Radek Sleha

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AIMS The aim of this study was to evaluate the antimicrobial effects of five natural substances against 50 clinical isolates of Mycoplasma hominis. METHODS AND RESULTS The in vitro activity of selected natural compounds, cinnamon bark oil, anethole, carvacrol, eugenol and guaiazulene, was investigated against 50 M. hominis isolates cultivated from(More)
Microorganisms which are present in the human urogenital tract may be involved in the development of inflammatory changes negatively affecting the genitals in both men and women. Pathological conditions due to inflammatory alterations may result in complete loss of fertility. Infections of the urogenital tract are responsible for 15% of all cases of(More)
The genetic diversity and epidemiology of VZV results from an interplay of the geographic area, climate conditions, and population factors. Studies of the genetic diversity of VZV can have direct implications for both the epidemiological and evolutionary analyses and identification of the genetic correlates of VZV pathogenicity or resistance to antiviral(More)
Varicella-zoster virus (VZV), herpes simplex virus one (HSV-1) and herpes simplex virus two (HSV-2) represent three out of the eight known human herpesviruses and belong to the subfamily of α-herpesviruses. These viruses are present worldwide and humans are their sole host and reservoir. After the primary infection, these viruses persist in the body(More)
Varicella zoster virus (VZV) is a highly contagious human pathogen. Virus causes varicella (chickenpox) as a primary infection during which a lifelong latent infection is established. It is easily passed through airborne particles, droplets in exhaled air and fluids from blisters or sores. Virus can be also transmitted indirectly by a contact with articles(More)
UNLABELLED Pathogenic species of the Legionella genus can cause respiratory diseases ranging in severity from benign Pontiac fever to life-threatening Legionnaires disease often characterized by severe pneumonia, high fever, and multiple organ involvement. Predisposing underlying conditions, such as immunosuppression, chronic lung disease, and malignancies(More)
The epidemiology of selected sexually transmitted diseases in the Czech Republic has been carefully evaluated for many years. Data from 1981-2011 for eastern Bohemia shows a sharp decrease in the incidence of gonorrhea in 1993-1994 and a very low incidence thereafter with a slightly higher prevalence in males. However, syphilis and genitourinary infections(More)
Neurosyphilis is defined as infection of central nervous system by Treponema pallidum subspecies pallidum. Neurosyphilis can develop at any stage after initial infec-tion and is reflected in laboratory results. The pathogenesis of neurosyphilis is similar to that of classical form of syphilis. Individuals with persistent abnormalities in the cerebrospinal(More)
The genus Enterococcus is represented by some of the clinically important species and is well known for its antibiotic resistance, which participates in colonization and infection. Increasing resistance of enterococci has been evoked due to the excessive use of antibiotics not merely for therapeutic purposes or in indicated cases. One of the promising(More)