Rachna Gupta

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Peroxisome proliferator-activated receptor-gamma (PPAR-γ) agonists (thiazolidinediones) are widely prescribed for the treatment of type-II diabetes mellitus. Recently, PPAR-γ agonists have shown neuroprotective effects in neurodegenerative disorders. The current study was carried out to investigate the effects of chronic administration of pioglitazone, a(More)
BACKGROUND Resveratrol (3,4',5-trihydroxystilbene) is a naturally occurring compound found in grapes, wine, peanuts and cranberries. Recently, in vitro and cell culture studies have reported beneficial effects of resveratrol in the neurodegenerative process in Alzheimer's disease (AD). However, in vivo effect of resveratrol in models of learning and memory(More)
Background: Resveratrol (3,4’,5-trihydroxystilbene) is a naturally occurring compound found in grapes, wine, peanuts and cranberries. Recently, in vitro and cell culture studies have reported beneficial effects of resveratrol in the neurodegenerative process in Alzheimer’s disease (AD). However, in vivo effect of resveratrol in models of learning and memory(More)
INTRODUCTION Burn injuries are a serious public health problem. In our study we have identified different epidemiological factors based on 10 years of our experience at a burn unit in central India and recommend some strategies to prevent burn injuries. MATERIALS AND METHODS This is a retrospective analysis (2001-2010) of database from burn unit of S.S.(More)
OBJECTIVE Good biomarkers are important to guide decisions in the clinical management of rheumatoid arthritis (RA). RA patients harbor antibodies directed against carbamylated proteins which may predict joint damage. This study investigated whether antibodies against carbamylated proteins (anti-CarP) may serve as surrogate prognostic markers. MATERIAL AND(More)
Glucagon-like peptide (GLP-1) receptor agonists and dipeptidyl peptidase 4 (DPP-4) inhibitors are two currently approved therapies for type 2 diabetes mellitus (T2DM). Present study evaluated the effect of liraglutide (a long-acting GLP-1 agonist) and sitagliptin (a DPP-4 inhibitor) on nociception, anxiety, depression-like behavior and cognition in rats or(More)
Modafinil [2-((diphenylmethyl) sulfinyl) acetamide] is a central nervous system stimulant. It has received considerable attention as a potential psychotropic agent in several psychiatric disorders. The current study was carried out to investigate the effect of modafinil after acute administration on animal models of pain in mice. Also, this study evaluated(More)
For the prevention of postoperative ocular infections prophylactic topical antibiotics are routinely used. Studies evaluating comparative difference between single dose versus multiple dose administration on aqueous humour concentration of moxifloxacin are lacking. This study compared the aqueous humour concentration of moxifloxacin following its topical(More)
Objectives: Premenstrual symptoms may affect quality of life (QoL) by negatively affecting behavior and interfering with daily activities in women. In this randomized placebo-controlled clinical trial performed in women with premenstrual syndrome (PMS), treatment with bromocriptine and pyridoxine was evaluated with respect to their impact on QoL. Methods:(More)
Quizzes are considered one of the more effective methods of learning and teaching as they promote self-learning and motivate students to be more attentive. The present study evaluated the impact of a quiz competition on learning behaviour of postgraduate students in pharmacology. Postgraduate students in pharmacology from medical (M.D.) and pharmaceutical(More)
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