Rachel T Williams

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It has been shown that ischaemic heart disease tends to be associated with elevated levels of serum cholesterol, both in populations (Keys et al., 1958) and in individuals (Kannel et al.,. 1961). There is also evidence that population levels of serum cholesterol are sometimes correlated with (among other characteristics) a high intake of animal fats and a(More)
This study was undertaken to investigate whether an exercise bout increases muscle protein degradation and amino acid catabolism. The excretion of urea and N tau -methylhistidine before and after an exercise bout was determined for both rats and human subjects. The rats ran on a treadmill until they could no longer run. Two groups of human subjects(More)
PURPOSE Early ambulation and rehabilitation are recommended for patients undergoing surgical fixation of hip fracture. Gait velocity may be used as an outcome measure for these patients during acute rehabilitation. As an outcome measure, an estimate of meaningful change (responsiveness) in gait velocity for these patients, however, has not been described.(More)
The metabolic fate of orally administered (−)-[14C]-ephedrine has been studied in 3 human subjects and the urinary excretion of metabolites determined quantitatively by solvent extraction, paper chromatography and reverse isotope dilution procedures. Following an oral dose of the drug (0.35 mg/kg, 1.6 µCi), 97% of the dose was excreted in the urine within(More)
The metabolism of (+)-[14C] amphetamine has been studied in two women who had been taking 90–100 mg of Dexedrine ((+)amphetamine sulphate; Smith, Kline & French) daily for several years but who showed no evidence of overt amphetamine toxicity. The urinary metabolites were identified, estimated and compared with the results previously obtained from two drug(More)