Rachel Patel

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Male reproductive glands secrete signals into seminal fluid to facilitate reproductive success. In Drosophila melanogaster, these signals are generated by a variety of seminal peptides, many produced by the accessory glands (AGs). One epithelial cell type in the adult male AGs, the secondary cell (SC), grows selectively in response to bone morphogenetic(More)
We describe a novel approach to study tumour progression and vasculature development in vivo via global 3-D fluorescence imaging of live non-pigmented adult zebrafish utilising angularly multiplexed optical projection tomography with compressive sensing (CS-OPT). This "mesoscopic" imaging method bridges a gap between established ~μm resolution 3-D(More)
A critical component of diagramming sketch tools is their ability to reliably recognise hand-drawn diagram components. This is made difficult by the presence of both geometric shapes and characters in diagrams. The goal of our research is to improve sketch recognition by improving the accuracy in grouping and classifying strokes in a diagram into text(More)
Common to all life on Earth are the mechanisms of genetic<lb>encoding, in which specific trinucleotide sequences in DNA<lb>and RNAmap to specific amino acids in synthesized proteins.<lb>This thesis project investigates feasible models of the evolu-<lb>tion of genetic encoding from an initially random population<lb>of genes and proteins. Discrete simulations(More)
BACKGROUND Unipolar depression is the third highest contributor to the global burden of disease, yet current pharmacotherapies typically take about 6 weeks to have an effect. A rapid-onset agent is an attractive prospect, not only to alleviate symptoms before first-line antidepressants display therapeutic action, but as a further treatment option in(More)
The Rockefeller University Press $30.00 J. Cell Biol. Vol. 206 No. 5 671–688 www.jcb.org/cgi/doi/10.1083/jcb.201401072 JCB 671 D.C.I. Goberdhan and C. Wilson contributed equally to this paper. Correspondence to Clive Wilson: clive.wilson@dpag.ox.ac.uk Abbreviations used in this paper: AG, accessory gland; ANCE, angiotensinconverting enzyme I; BMP, bone(More)
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