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Yes‐Associated Protein is up‐regulated by mechanical overload and is sufficient to induce skeletal muscle hypertrophy
Mechanically‐induced skeletal muscle growth is regulated by mammalian/mechanistic target of rapamycin complex 1 (mTORC1). Yes‐Associated Protein (YAP) is a mechanically‐sensitive, and growth‐related,Expand
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A map of the phosphoproteomic alterations that occur after a bout of maximal‐intensity contractions
Mechanical signals play a critical role in the regulation of muscle mass, but the molecules that sense mechanical signals and convert this stimulus into the biochemical events that regulate muscleExpand
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The role of raptor in the mechanical load‐induced regulation of mTOR signaling, protein synthesis, and skeletal muscle hypertrophy
It is well known that an increase in mechanical loading can induce skeletal muscle hypertrophy, and a long standing model in the field indicates that mechanical loads induce hypertrophy via aExpand
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Smad3 induces atrogin-1, inhibits mTOR and protein synthesis, and promotes muscle atrophy in vivo.
Myostatin, a member of the TGF superfamily, is sufficient to induce skeletal muscle atrophy. Myostatin-induced atrophy is associated with increases in E3-ligase atrogin-1 expression and proteinExpand
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Identification of mechanically regulated phosphorylation sites on tuberin (TSC2) that control mechanistic target of rapamycin (mTOR) signaling
Mechanistic target of rapamycin (mTOR) signaling is necessary to generate a mechanically induced increase in skeletal muscle mass, but the mechanism(s) through which mechanical stimuli regulate mTORExpand
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Effects of oral phosphatidic acid feeding with or without whey protein on muscle protein synthesis and anabolic signaling in rodent skeletal muscle
BackgroundPhosphatidic acid (PA) is a diacyl-glycerophospholipid that acts as a signaling molecule in numerous cellular processes. Recently, PA has been proposed to stimulate skeletal muscle proteinExpand
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Common European Asylum System: Contradictions and Crises
This paper exposes the contradictions and lack of commonality in the Common European Asylum System (CEAS), as well as the wide discrepancy between the European Union’s (EU) human rights rhetoric andExpand
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40 Days and 40 Nights
Rachel McNally invesitigates Lent practices and lessons, and their impact on social relations.
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