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Hydrogel polymers consisting of HEMA (2-hydroxyethyl methacrylate) alone or co-polymerized with NVP N-(vinyl pyrrolidone) were incorporated into silicone rubber tubing to produce hydrophilic composite materials. Polymerization methods of the interpenetrating network (IPN) and radiation-induced type were used to impregnate the silicone rubber substrates.(More)
Three hydrogel formulations consisting of 2-hydroxyethyl methacrylate (HEMA) copolymerized with N-vinyl pyrrolidone (NVP) were incorporated into silicone rubber by irradiation-induced polymerization. These coatings were chosen to represent different degrees of hydrophilicity, and they changed the hydrophobic character of the silicone rubber surface to that(More)
Ring shaped ocular inserts have been developed to administer a therapeutic level of tylosin tartrate throughout a five day period to treat pinkeye in cattle. The inserts are based on polyvinyl chloride rings which are dip coated with a copolymer containing the antibiotic (tylosin tartrate). Scanning electron microscope (SEM) characterization of surfaces has(More)
Luminescence measurements of Tranquillity samples indicate that energy efficiencies for excitation by protons and ultraviolet are in the range 10(-6) or below; natural and induced thermoluminescence is even weaker. If these samples are typical, lunar surface luminescence cannot occur at reported levels. Comparison of proton luminescence spectra from the(More)
Samples of an antibiotic released from an ocular insert in an in vitro test are characterized by thin layer chromatography (TLC). Conventional characterization methods include cutting and weighing strip chart paper peak profiles obtained with a scanning densitometer for spotted TLC plates, and relating peaks for unknowns to peaks for standards on the basis(More)
Two types of polyethylene terephthalate (Dacron) substrates (USCI DeBakey Vasculour-D and USCI Sauvage filamentous) have been selectively coated with Poly-hydroxyethyl methacrylate (P-HEMA) in a two-stage process. Using scanning electon microscopy (SEM) techniques, the microstructural details of the fabrications were identified. The first stage of this(More)
Aim: The Chemotherapy and Pharmacy Advisory Service (CPAS) was established in 2007 by the UK National Cancer Research Network (NCRN) to improve the quality of pharmacy-related issues in clinical research protocols. We report the scope and methodology of the CPAS, and its impact on the quality of clinical research protocols. Methods: All clinical research(More)
AIM Clarity and accuracy of the pharmacy aspects of cancer clinical trial protocols is essential. Inconsistencies and ambiguities in protocols have the potential to delay research and jeopardise both patient safety and the collection of credible data. The Chemotherapy and Pharmacy Advisory Service (CPAS) was established in 2007 by the UK National Cancer(More)