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The generation of chromosomal deletions to provide extensive coverage and subdivision of the Drosophila melanogaster genome
BackgroundChromosomal deletions are used extensively in Drosophila melanogaster genetics research. Deletion mapping is the primary method used for fine-scale gene localization. Effective and… Expand
Genetic basis for a rare floral mutant in an Andean species of Solanaceae.
PREMISE OF THE STUDY White forms of typically pigmented flowers are one of the most common polymorphisms in flowering plants. Although the range of genetic changes that give rise to white phenotypes… Expand
HDAC1 Is a Required Cofactor of CBFβ-SMMHC and a Potential Therapeutic Target in Inversion 16 Acute Myeloid Leukemia
- L. Richter, Y. Wang, +4 authors R. K. Hyde
- Chemistry, Medicine
- Molecular Cancer Research
- 27 February 2019
Acute myeloid leukemia (AML) is a neoplastic disease characterized by the uncontrolled proliferation and accumulation of immature myeloid cells. A common mutation in AML is the inversion of… Expand